Development of a Synthetic 3‑Dehydroshikimate Biosensor in Escherichia coli for Metabolite Monitoring and Genetic Screening

Biosensors for target metabolites provide powerful high-throughput screening tools to obtain high-performing strains. However, well-characterized metabolite-sensing modules are often unavailable and limit rapid access to the robust biosensors with successful applications. In this study, we developed...

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Veröffentlicht in:	ACS synthetic biology 2019-02, Vol.8 (2), p.297-306
Hauptverfasser:	Li, Liangpo, Tu, Ran, Song, Guotian, Cheng, Jie, Chen, Wujiu, Li, Lin, Wang, Lixian, Wang, Qinhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques Escherichia coli - metabolism Gene Expression Regulation - genetics Metabolic Engineering - methods Shikimic Acid - analogs & derivatives Transcription Factors - metabolism Transcriptome - genetics
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