Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015
Background Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce. Methods We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000–2015. Results A...
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| Veröffentlicht in: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2019-07, Vol.22 (4), p.675-683 |
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| creator | Braga, Lucia Libanez Bessa Campelo Ramos, Alberto Novaes Braga Neto, Manuel Bonfim Ferreira, Anderson Fuentes Queiroz, Dulciene Maria Magalhães Maia, Danielle Calheiros Campelo Alencar, Carlos Henrique Heukelbach, Jorg |
| description | Background
Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce.
Methods
We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000–2015.
Results
A total of 17,374,134 deaths were recorded, with GC identified in 214,808 (1.24%) cases—203,941 (94.9%) as underlying cause, and 10,867 (5.1%) as associated cause of death. Adjusted rates for age and sex was 6.85 deaths/100,000 inhabitants [95% confidence interval (CI) 6.73–6.97]. The highest mortality rates were found in males [10.00; rate ratio (RR) 1.85; 95% CI 1.78–1.91;
p
|
| doi_str_mv | 10.1007/s10120-018-00916-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2163009434</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2240196060</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-aeb18fdb5830addaf35f04c0ec1377e3b0aff7ce11e6a1251633ddaa1d5de333</originalsourceid><addsrcrecordid>eNp9kc1O3TAQhS1EVSjtC7CoLLFh0bQznsRJlgX1T0LqhnZrOc74KihxwE4WsOIdeMM-SU0vP1IXrGzJ3zljzSfEIcJHBKg_JQRUUAA2BUCLutA7Yh9L0gURVLuPd9XinniT0gUAVhl7LfYINFCLsC9-_wp8tdpRdmvsOcjZy2mOix2H5Vr6OE9yY9MSByedDY6jHII8ifZmGKUNvRyWJCNvhjmkD1IBwJ_bO5XHvBWvvB0Tv3s4D8T51y_np9-Ls5_ffpx-Pitc2TZLYbnDxvdd1RDYvreeKg-lA3ZIdc3UgfW-dozI2qKqUBNlzGJf9UxEB-J4W3sZ56uV02KmITkeRxt4XpNROZBXU1KZ0aP_0It5jSF_zihVArb6ficvUaiVrqlsMFNqS7k4pxTZm8s4TDZeGwRzr8Zs1ZisxvxTY3QOvX-oXruJ-6fIo4sM0BZI-SlsOD7PfqH2L9Ucl48</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2162673481</pqid></control><display><type>article</type><title>Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Springer Nature - Complete Springer Journals</source><creator>Braga, Lucia Libanez Bessa Campelo ; Ramos, Alberto Novaes ; Braga Neto, Manuel Bonfim ; Ferreira, Anderson Fuentes ; Queiroz, Dulciene Maria Magalhães ; Maia, Danielle Calheiros Campelo ; Alencar, Carlos Henrique ; Heukelbach, Jorg</creator><creatorcontrib>Braga, Lucia Libanez Bessa Campelo ; Ramos, Alberto Novaes ; Braga Neto, Manuel Bonfim ; Ferreira, Anderson Fuentes ; Queiroz, Dulciene Maria Magalhães ; Maia, Danielle Calheiros Campelo ; Alencar, Carlos Henrique ; Heukelbach, Jorg</creatorcontrib><description>Background
Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce.
Methods
We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000–2015.
Results
A total of 17,374,134 deaths were recorded, with GC identified in 214,808 (1.24%) cases—203,941 (94.9%) as underlying cause, and 10,867 (5.1%) as associated cause of death. Adjusted rates for age and sex was 6.85 deaths/100,000 inhabitants [95% confidence interval (CI) 6.73–6.97]. The highest mortality rates were found in males [10.00; rate ratio (RR) 1.85; 95% CI 1.78–1.91;
p
< 0.0001] and patients ≥ 45 years of age (24.98; RR 3.79; 95% CI 3.55–4.05;
p
< 0.0001). The South (7.56; RR 1.62; 95% CI 1.50–1.76;
p
< 0.0001) and Southeast (7.36; RR 1.59; 95% CI 1.48–1.71;
p
< 0.0001) regions had the highest regional rates. Spatial and spatiotemporal high-risk mortality areas in 2004–2007 were located mainly in the South, Southeast, and Central-West regions. After 2008, the Northeast region became a high-risk area, especially Ceará State.
Conclusion
GC remains a significant public health problem with high mortality burden and unequal distribution in Brazilian states. The new patterns in poorer regions and the high risk in some specific populations show a clear process of epidemiological transition over time. There is a need to strengthen nationwide epidemiological monitoring, surveillance, prevention, and control for GC in the country.</description><identifier>ISSN: 1436-3291</identifier><identifier>EISSN: 1436-3305</identifier><identifier>DOI: 10.1007/s10120-018-00916-6</identifier><identifier>PMID: 30603910</identifier><language>eng</language><publisher>Singapore: Springer Singapore</publisher><subject>Abdominal Surgery ; Adolescent ; Adult ; Age Factors ; Aged ; Brazil - epidemiology ; Cancer Research ; Demography ; Epidemiology ; Female ; Follow-Up Studies ; Gastric cancer ; Gastroenterology ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Morbidity ; Mortality ; Oncology ; Original Article ; Prognosis ; Public health ; Sex Factors ; Spatial distribution ; Stomach Neoplasms - epidemiology ; Stomach Neoplasms - mortality ; Surgical Oncology ; Survival Rate ; Time Factors ; Young Adult</subject><ispartof>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019-07, Vol.22 (4), p.675-683</ispartof><rights>The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2019</rights><rights>Gastric Cancer is a copyright of Springer, (2019). All Rights Reserved.</rights><rights>Copyright Springer Nature B.V. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-aeb18fdb5830addaf35f04c0ec1377e3b0aff7ce11e6a1251633ddaa1d5de333</citedby><cites>FETCH-LOGICAL-c498t-aeb18fdb5830addaf35f04c0ec1377e3b0aff7ce11e6a1251633ddaa1d5de333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10120-018-00916-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10120-018-00916-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27915,27916,41479,42548,51310</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30603910$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Braga, Lucia Libanez Bessa Campelo</creatorcontrib><creatorcontrib>Ramos, Alberto Novaes</creatorcontrib><creatorcontrib>Braga Neto, Manuel Bonfim</creatorcontrib><creatorcontrib>Ferreira, Anderson Fuentes</creatorcontrib><creatorcontrib>Queiroz, Dulciene Maria Magalhães</creatorcontrib><creatorcontrib>Maia, Danielle Calheiros Campelo</creatorcontrib><creatorcontrib>Alencar, Carlos Henrique</creatorcontrib><creatorcontrib>Heukelbach, Jorg</creatorcontrib><title>Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015</title><title>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</title><addtitle>Gastric Cancer</addtitle><addtitle>Gastric Cancer</addtitle><description>Background
Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce.
Methods
We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000–2015.
Results
A total of 17,374,134 deaths were recorded, with GC identified in 214,808 (1.24%) cases—203,941 (94.9%) as underlying cause, and 10,867 (5.1%) as associated cause of death. Adjusted rates for age and sex was 6.85 deaths/100,000 inhabitants [95% confidence interval (CI) 6.73–6.97]. The highest mortality rates were found in males [10.00; rate ratio (RR) 1.85; 95% CI 1.78–1.91;
p
< 0.0001] and patients ≥ 45 years of age (24.98; RR 3.79; 95% CI 3.55–4.05;
p
< 0.0001). The South (7.56; RR 1.62; 95% CI 1.50–1.76;
p
< 0.0001) and Southeast (7.36; RR 1.59; 95% CI 1.48–1.71;
p
< 0.0001) regions had the highest regional rates. Spatial and spatiotemporal high-risk mortality areas in 2004–2007 were located mainly in the South, Southeast, and Central-West regions. After 2008, the Northeast region became a high-risk area, especially Ceará State.
Conclusion
GC remains a significant public health problem with high mortality burden and unequal distribution in Brazilian states. The new patterns in poorer regions and the high risk in some specific populations show a clear process of epidemiological transition over time. There is a need to strengthen nationwide epidemiological monitoring, surveillance, prevention, and control for GC in the country.</description><subject>Abdominal Surgery</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Brazil - epidemiology</subject><subject>Cancer Research</subject><subject>Demography</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastric cancer</subject><subject>Gastroenterology</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Prognosis</subject><subject>Public health</subject><subject>Sex Factors</subject><subject>Spatial distribution</subject><subject>Stomach Neoplasms - epidemiology</subject><subject>Stomach Neoplasms - mortality</subject><subject>Surgical Oncology</subject><subject>Survival Rate</subject><subject>Time Factors</subject><subject>Young Adult</subject><issn>1436-3291</issn><issn>1436-3305</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kc1O3TAQhS1EVSjtC7CoLLFh0bQznsRJlgX1T0LqhnZrOc74KihxwE4WsOIdeMM-SU0vP1IXrGzJ3zljzSfEIcJHBKg_JQRUUAA2BUCLutA7Yh9L0gURVLuPd9XinniT0gUAVhl7LfYINFCLsC9-_wp8tdpRdmvsOcjZy2mOix2H5Vr6OE9yY9MSByedDY6jHII8ifZmGKUNvRyWJCNvhjmkD1IBwJ_bO5XHvBWvvB0Tv3s4D8T51y_np9-Ls5_ffpx-Pitc2TZLYbnDxvdd1RDYvreeKg-lA3ZIdc3UgfW-dozI2qKqUBNlzGJf9UxEB-J4W3sZ56uV02KmITkeRxt4XpNROZBXU1KZ0aP_0It5jSF_zihVArb6ficvUaiVrqlsMFNqS7k4pxTZm8s4TDZeGwRzr8Zs1ZisxvxTY3QOvX-oXruJ-6fIo4sM0BZI-SlsOD7PfqH2L9Ucl48</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Braga, Lucia Libanez Bessa Campelo</creator><creator>Ramos, Alberto Novaes</creator><creator>Braga Neto, Manuel Bonfim</creator><creator>Ferreira, Anderson Fuentes</creator><creator>Queiroz, Dulciene Maria Magalhães</creator><creator>Maia, Danielle Calheiros Campelo</creator><creator>Alencar, Carlos Henrique</creator><creator>Heukelbach, Jorg</creator><general>Springer Singapore</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20190701</creationdate><title>Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015</title><author>Braga, Lucia Libanez Bessa Campelo ; Ramos, Alberto Novaes ; Braga Neto, Manuel Bonfim ; Ferreira, Anderson Fuentes ; Queiroz, Dulciene Maria Magalhães ; Maia, Danielle Calheiros Campelo ; Alencar, Carlos Henrique ; Heukelbach, Jorg</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-aeb18fdb5830addaf35f04c0ec1377e3b0aff7ce11e6a1251633ddaa1d5de333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Abdominal Surgery</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Brazil - epidemiology</topic><topic>Cancer Research</topic><topic>Demography</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastric cancer</topic><topic>Gastroenterology</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Prognosis</topic><topic>Public health</topic><topic>Sex Factors</topic><topic>Spatial distribution</topic><topic>Stomach Neoplasms - epidemiology</topic><topic>Stomach Neoplasms - mortality</topic><topic>Surgical Oncology</topic><topic>Survival Rate</topic><topic>Time Factors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Braga, Lucia Libanez Bessa Campelo</creatorcontrib><creatorcontrib>Ramos, Alberto Novaes</creatorcontrib><creatorcontrib>Braga Neto, Manuel Bonfim</creatorcontrib><creatorcontrib>Ferreira, Anderson Fuentes</creatorcontrib><creatorcontrib>Queiroz, Dulciene Maria Magalhães</creatorcontrib><creatorcontrib>Maia, Danielle Calheiros Campelo</creatorcontrib><creatorcontrib>Alencar, Carlos Henrique</creatorcontrib><creatorcontrib>Heukelbach, Jorg</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Braga, Lucia Libanez Bessa Campelo</au><au>Ramos, Alberto Novaes</au><au>Braga Neto, Manuel Bonfim</au><au>Ferreira, Anderson Fuentes</au><au>Queiroz, Dulciene Maria Magalhães</au><au>Maia, Danielle Calheiros Campelo</au><au>Alencar, Carlos Henrique</au><au>Heukelbach, Jorg</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015</atitle><jtitle>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</jtitle><stitle>Gastric Cancer</stitle><addtitle>Gastric Cancer</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>22</volume><issue>4</issue><spage>675</spage><epage>683</epage><pages>675-683</pages><issn>1436-3291</issn><eissn>1436-3305</eissn><abstract>Background
Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce.
Methods
We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000–2015.
Results
A total of 17,374,134 deaths were recorded, with GC identified in 214,808 (1.24%) cases—203,941 (94.9%) as underlying cause, and 10,867 (5.1%) as associated cause of death. Adjusted rates for age and sex was 6.85 deaths/100,000 inhabitants [95% confidence interval (CI) 6.73–6.97]. The highest mortality rates were found in males [10.00; rate ratio (RR) 1.85; 95% CI 1.78–1.91;
p
< 0.0001] and patients ≥ 45 years of age (24.98; RR 3.79; 95% CI 3.55–4.05;
p
< 0.0001). The South (7.56; RR 1.62; 95% CI 1.50–1.76;
p
< 0.0001) and Southeast (7.36; RR 1.59; 95% CI 1.48–1.71;
p
< 0.0001) regions had the highest regional rates. Spatial and spatiotemporal high-risk mortality areas in 2004–2007 were located mainly in the South, Southeast, and Central-West regions. After 2008, the Northeast region became a high-risk area, especially Ceará State.
Conclusion
GC remains a significant public health problem with high mortality burden and unequal distribution in Brazilian states. The new patterns in poorer regions and the high risk in some specific populations show a clear process of epidemiological transition over time. There is a need to strengthen nationwide epidemiological monitoring, surveillance, prevention, and control for GC in the country.</abstract><cop>Singapore</cop><pub>Springer Singapore</pub><pmid>30603910</pmid><doi>10.1007/s10120-018-00916-6</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019-07, Vol.22 (4), p.675-683 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Springer Nature - Complete Springer Journals |
| subjects | Abdominal Surgery Adolescent Adult Age Factors Aged Brazil - epidemiology Cancer Research Demography Epidemiology Female Follow-Up Studies Gastric cancer Gastroenterology Humans Male Medicine Medicine & Public Health Middle Aged Morbidity Mortality Oncology Original Article Prognosis Public health Sex Factors Spatial distribution Stomach Neoplasms - epidemiology Stomach Neoplasms - mortality Surgical Oncology Survival Rate Time Factors Young Adult |
| title | Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015 |
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