Association of a Noncoding RNA Postmortem With Suicide by Violent Means and In Vivo With Aggressive Phenotypes

Previous findings suggest that differences in brain expression of a human-specific long intergenic noncoding RNA (LINC01268; GRCh37/hg19: LOC285758) may be linked to suicide by violent methods. We sought to replicate and extend these findings in a new sample and translate the results to the behavior...

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Veröffentlicht in:	Biological psychiatry (1969) 2019-03, Vol.85 (5), p.417-424
Hauptverfasser:	Punzi, Giovanna, Ursini, Gianluca, Viscanti, Giovanna, Radulescu, Eugenia, Shin, Joo Heon, Quarto, Tiziana, Catanesi, Roberto, Blasi, Giuseppe, Jaffe, Andrew E., Deep-Soboslay, Amy, Hyde, Thomas M., Kleinman, Joel E., Bertolino, Alessandro, Weinberger, Daniel R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aggression Aggression - physiology Brain Brain - metabolism Cause of Death Female Functional Neuroimaging Gene Regulatory Networks - genetics Genotype Humans Magnetic Resonance Imaging Male Mental Disorders - genetics Mental Disorders - physiopathology Mental Disorders - psychology Phenotype Postmortem Prefrontal Cortex - physiology RNA, Untranslated - biosynthesis RNA, Untranslated - physiology RNA-seq Sequence Analysis, RNA Suicide Suicide - psychology Suicide methods Violence
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