In vivo evaluation of anticancer efficacy of drug loaded cockle shell‐derived aragonite nanoparticles

Doxorubicin (DOX) is an effective and commonly used anthracycline anticancer drug for the treatment of osteosarcoma (OS). However, its antitumor effect is hampered by the nonspecific distribution and significant adverse effects. Nanoparticles based drug delivery systems are promising approaches to m...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2019-08, Vol.107 (6), p.1898-1907
Hauptverfasser:	Wenliang, Fu, Rameli, Mohd Adha bin P., Ibrahim, Tengku Azmi Tengku, Noor, Mohd Hezmee Mohd, Yusof, Loqman Mohamad, Zakaria, Md Zuki Abu Bakar
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthracycline Anticancer properties Antitumor activity Aragonite Biocompatibility Biomedical materials Bone cancer calcium carbonate Cancer Chemotherapy Doxorubicin Drug delivery Drug delivery systems Effectiveness Equivalence Materials research Materials science Nanoparticles Organs Osteosarcoma Sarcoma Shells Side effects Tibia Toxicity
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