Impact of Coronary Revascularization in Patients Who Underwent Transcatheter Aortic Valve Implantation
Coronary artery disease (CAD) is a common co-morbidity in transcatheter aortic valve implantation (TAVI) patients, but the prognostic value of coronary revascularization before TAVI is currently unknown. The aim of the present study was to assess the impact of coronary revascularization in patients...
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| Veröffentlicht in: | The American journal of cardiology 2019-03, Vol.123 (6), p.948-955 |
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| creator | López Otero, Diego Ávila-Carrillo, Alejandro González Ferreiro, Rocío Cid Menéndez, Adrián Iglesias Álvarez, Diego Álvarez Rodríguez, Leyre Antúnez Muiños, Pablo Álvarez, Belén Cid Sanmartín Pena, Xoan Carlos Gómez Pérez, Fernando Diéguez, Alfredo Redondo Cruz-González, Ignacio Trillo Nouche, Ramiro González-Juanatey, José Ramón |
| description | Coronary artery disease (CAD) is a common co-morbidity in transcatheter aortic valve implantation (TAVI) patients, but the prognostic value of coronary revascularization before TAVI is currently unknown. The aim of the present study was to assess the impact of coronary revascularization in patients who underwent TAVI. Patients underwent TAVI from 2008 to 2016 were included in the study. Baseline SYNTAX score and residual SYNTAX score (rSS) after percutaneous coronary intervention were calculated. Based on rSS, patients were classified as complete revascularization (rSS = 0), reasonably incomplete revascularization (rSS >0 and |
| doi_str_mv | 10.1016/j.amjcard.2018.12.007 |
| format | Article |
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The aim of the present study was to assess the impact of coronary revascularization in patients who underwent TAVI. Patients underwent TAVI from 2008 to 2016 were included in the study. Baseline SYNTAX score and residual SYNTAX score (rSS) after percutaneous coronary intervention were calculated. Based on rSS, patients were classified as complete revascularization (rSS = 0), reasonably incomplete revascularization (rSS >0 and <8), and incomplete revascularization (rSS ≥8). The primary objective was to evaluate the impact of CAD and rSS on major cardiovascular adverse events (MACEs). The secondary objective was to assess the impact of rSS on hospitalization for heart failure. A total of 349 patients (mean age 82.4 ± 5.7 years, 53% women) were included in the study. A total of 187 patients (53.6%) had CAD (mean baseline SYNTAX score 9.2 ± 8.1). Percutaneous coronary intervention was performed in 29.9% of patients, achieving reasonably incomplete revascularization in 45.4%, and incomplete revascularization in 24.5%. The mean follow-up was 35.2 ± 25.3 months. No differences were observed in MACE rate between the CAD and non-CAD groups, or between the different degrees of revascularization. Differences were also not seen in the different levels of revascularization and hospitalization due to heart failure. In patients who underwent TAVI in this study, no association was found between the presence of CAD or the degree of revascularization in a long-term follow-up.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2018.12.007</identifier><identifier>PMID: 30598242</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged, 80 and over ; Aortic valve ; Aortic Valve Stenosis - diagnosis ; Aortic Valve Stenosis - epidemiology ; Aortic Valve Stenosis - surgery ; Cardiology ; Cardiovascular disease ; Clinical medicine ; Comorbidity ; Congestive heart failure ; Coronary Angiography ; Coronary artery ; Coronary artery disease ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - epidemiology ; Coronary Artery Disease - surgery ; Coronary vessels ; Echocardiography ; Female ; Follow-Up Studies ; Heart ; Heart failure ; Humans ; Implantation ; Intervention ; Male ; Medical prognosis ; Morbidity ; Patients ; Percutaneous Coronary Intervention - methods ; Prognosis ; Registries ; Retrospective Studies ; Rheumatic heart disease ; Risk Assessment - methods ; Risk Factors ; Severity of Illness Index ; Spain - epidemiology ; Stents ; Survival Rate - trends ; Syntax ; Time Factors ; Transcatheter Aortic Valve Replacement - methods ; Transplants & implants ; Variables</subject><ispartof>The American journal of cardiology, 2019-03, Vol.123 (6), p.948-955</ispartof><rights>2018 Elsevier Inc.</rights><rights>Copyright © 2018 Elsevier Inc. All rights reserved.</rights><rights>2018. Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-b3922eb0dbe2d0c0273e56f75e7fe8fc6739299347ab30cbff5f6e1f1fe340fc3</citedby><cites>FETCH-LOGICAL-c393t-b3922eb0dbe2d0c0273e56f75e7fe8fc6739299347ab30cbff5f6e1f1fe340fc3</cites><orcidid>0000-0001-8312-4874</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2185592345?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30598242$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>López Otero, Diego</creatorcontrib><creatorcontrib>Ávila-Carrillo, Alejandro</creatorcontrib><creatorcontrib>González Ferreiro, Rocío</creatorcontrib><creatorcontrib>Cid Menéndez, Adrián</creatorcontrib><creatorcontrib>Iglesias Álvarez, Diego</creatorcontrib><creatorcontrib>Álvarez Rodríguez, Leyre</creatorcontrib><creatorcontrib>Antúnez Muiños, Pablo</creatorcontrib><creatorcontrib>Álvarez, Belén Cid</creatorcontrib><creatorcontrib>Sanmartín Pena, Xoan Carlos</creatorcontrib><creatorcontrib>Gómez Pérez, Fernando</creatorcontrib><creatorcontrib>Diéguez, Alfredo Redondo</creatorcontrib><creatorcontrib>Cruz-González, Ignacio</creatorcontrib><creatorcontrib>Trillo Nouche, Ramiro</creatorcontrib><creatorcontrib>González-Juanatey, José Ramón</creatorcontrib><title>Impact of Coronary Revascularization in Patients Who Underwent Transcatheter Aortic Valve Implantation</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Coronary artery disease (CAD) is a common co-morbidity in transcatheter aortic valve implantation (TAVI) patients, but the prognostic value of coronary revascularization before TAVI is currently unknown. The aim of the present study was to assess the impact of coronary revascularization in patients who underwent TAVI. Patients underwent TAVI from 2008 to 2016 were included in the study. Baseline SYNTAX score and residual SYNTAX score (rSS) after percutaneous coronary intervention were calculated. Based on rSS, patients were classified as complete revascularization (rSS = 0), reasonably incomplete revascularization (rSS >0 and <8), and incomplete revascularization (rSS ≥8). The primary objective was to evaluate the impact of CAD and rSS on major cardiovascular adverse events (MACEs). The secondary objective was to assess the impact of rSS on hospitalization for heart failure. A total of 349 patients (mean age 82.4 ± 5.7 years, 53% women) were included in the study. A total of 187 patients (53.6%) had CAD (mean baseline SYNTAX score 9.2 ± 8.1). Percutaneous coronary intervention was performed in 29.9% of patients, achieving reasonably incomplete revascularization in 45.4%, and incomplete revascularization in 24.5%. The mean follow-up was 35.2 ± 25.3 months. No differences were observed in MACE rate between the CAD and non-CAD groups, or between the different degrees of revascularization. Differences were also not seen in the different levels of revascularization and hospitalization due to heart failure. In patients who underwent TAVI in this study, no association was found between the presence of CAD or the degree of revascularization in a long-term follow-up.</description><subject>Aged, 80 and over</subject><subject>Aortic valve</subject><subject>Aortic Valve Stenosis - diagnosis</subject><subject>Aortic Valve Stenosis - epidemiology</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Clinical medicine</subject><subject>Comorbidity</subject><subject>Congestive heart failure</subject><subject>Coronary Angiography</subject><subject>Coronary artery</subject><subject>Coronary artery disease</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Coronary Artery Disease - surgery</subject><subject>Coronary vessels</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Heart failure</subject><subject>Humans</subject><subject>Implantation</subject><subject>Intervention</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Morbidity</subject><subject>Patients</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>Prognosis</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Rheumatic heart disease</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Spain - epidemiology</subject><subject>Stents</subject><subject>Survival Rate - trends</subject><subject>Syntax</subject><subject>Time Factors</subject><subject>Transcatheter Aortic Valve Replacement - methods</subject><subject>Transplants & implants</subject><subject>Variables</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU9P3DAQxS1UBAvlI7Sy1EsvCf4TJ_EJoVVLkZCoKihHy3HGwlESb21nUfvpa9htD1w4zYz0mzej9xD6QElJCa3Ph1JPg9GhLxmhbUlZSUhzgFa0bWRBJeXv0IoQwgpJK3mMTmIc8kipqI_QMSdCtqxiK2Svp402CXuL1z74WYff-AdsdTTLqIP7o5PzM3Yz_p47mFPED48e3889hKc84rug52h0eoQEAV_6kJzBP_W4BZyVRz2nF4X36NDqMcLZvp6i-69f7tbfipvbq-v15U1huOSp6LhkDDrSd8B6YghrOIjaNgIaC601dZMBKXnV6I4T01krbA3UUgu8ItbwU_R5p7sJ_tcCManJRQNjfgT8EhWjNask5xXN6KdX6OCXMOfvMtUKIRmvRKbEjjLBxxjAqk1wU3ZJUaKeg1CD2gehnoNQlKkcRN77uFdfugn6_1v_nM_AxQ6AbMfWQVDRZIMN9C6ASar37o0TfwGc951n</recordid><startdate>20190315</startdate><enddate>20190315</enddate><creator>López Otero, Diego</creator><creator>Ávila-Carrillo, Alejandro</creator><creator>González Ferreiro, Rocío</creator><creator>Cid Menéndez, Adrián</creator><creator>Iglesias Álvarez, Diego</creator><creator>Álvarez Rodríguez, Leyre</creator><creator>Antúnez Muiños, Pablo</creator><creator>Álvarez, Belén Cid</creator><creator>Sanmartín Pena, Xoan Carlos</creator><creator>Gómez Pérez, Fernando</creator><creator>Diéguez, Alfredo Redondo</creator><creator>Cruz-González, Ignacio</creator><creator>Trillo Nouche, Ramiro</creator><creator>González-Juanatey, José Ramón</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8312-4874</orcidid></search><sort><creationdate>20190315</creationdate><title>Impact of Coronary Revascularization in Patients Who Underwent Transcatheter Aortic Valve Implantation</title><author>López Otero, Diego ; Ávila-Carrillo, Alejandro ; González Ferreiro, Rocío ; Cid Menéndez, Adrián ; Iglesias Álvarez, Diego ; Álvarez Rodríguez, Leyre ; Antúnez Muiños, Pablo ; Álvarez, Belén Cid ; Sanmartín Pena, Xoan Carlos ; Gómez Pérez, Fernando ; Diéguez, Alfredo Redondo ; Cruz-González, Ignacio ; Trillo Nouche, Ramiro ; González-Juanatey, José Ramón</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-b3922eb0dbe2d0c0273e56f75e7fe8fc6739299347ab30cbff5f6e1f1fe340fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged, 80 and over</topic><topic>Aortic valve</topic><topic>Aortic Valve Stenosis - 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methods</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Spain - epidemiology</topic><topic>Stents</topic><topic>Survival Rate - trends</topic><topic>Syntax</topic><topic>Time Factors</topic><topic>Transcatheter Aortic Valve Replacement - methods</topic><topic>Transplants & implants</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>López Otero, Diego</creatorcontrib><creatorcontrib>Ávila-Carrillo, Alejandro</creatorcontrib><creatorcontrib>González Ferreiro, Rocío</creatorcontrib><creatorcontrib>Cid Menéndez, Adrián</creatorcontrib><creatorcontrib>Iglesias Álvarez, Diego</creatorcontrib><creatorcontrib>Álvarez Rodríguez, Leyre</creatorcontrib><creatorcontrib>Antúnez Muiños, Pablo</creatorcontrib><creatorcontrib>Álvarez, Belén Cid</creatorcontrib><creatorcontrib>Sanmartín Pena, Xoan Carlos</creatorcontrib><creatorcontrib>Gómez Pérez, Fernando</creatorcontrib><creatorcontrib>Diéguez, Alfredo Redondo</creatorcontrib><creatorcontrib>Cruz-González, Ignacio</creatorcontrib><creatorcontrib>Trillo Nouche, Ramiro</creatorcontrib><creatorcontrib>González-Juanatey, José Ramón</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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The aim of the present study was to assess the impact of coronary revascularization in patients who underwent TAVI. Patients underwent TAVI from 2008 to 2016 were included in the study. Baseline SYNTAX score and residual SYNTAX score (rSS) after percutaneous coronary intervention were calculated. Based on rSS, patients were classified as complete revascularization (rSS = 0), reasonably incomplete revascularization (rSS >0 and <8), and incomplete revascularization (rSS ≥8). The primary objective was to evaluate the impact of CAD and rSS on major cardiovascular adverse events (MACEs). The secondary objective was to assess the impact of rSS on hospitalization for heart failure. A total of 349 patients (mean age 82.4 ± 5.7 years, 53% women) were included in the study. A total of 187 patients (53.6%) had CAD (mean baseline SYNTAX score 9.2 ± 8.1). Percutaneous coronary intervention was performed in 29.9% of patients, achieving reasonably incomplete revascularization in 45.4%, and incomplete revascularization in 24.5%. The mean follow-up was 35.2 ± 25.3 months. No differences were observed in MACE rate between the CAD and non-CAD groups, or between the different degrees of revascularization. Differences were also not seen in the different levels of revascularization and hospitalization due to heart failure. In patients who underwent TAVI in this study, no association was found between the presence of CAD or the degree of revascularization in a long-term follow-up.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30598242</pmid><doi>10.1016/j.amjcard.2018.12.007</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-8312-4874</orcidid></addata></record> |
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| subjects | Aged, 80 and over Aortic valve Aortic Valve Stenosis - diagnosis Aortic Valve Stenosis - epidemiology Aortic Valve Stenosis - surgery Cardiology Cardiovascular disease Clinical medicine Comorbidity Congestive heart failure Coronary Angiography Coronary artery Coronary artery disease Coronary Artery Disease - diagnosis Coronary Artery Disease - epidemiology Coronary Artery Disease - surgery Coronary vessels Echocardiography Female Follow-Up Studies Heart Heart failure Humans Implantation Intervention Male Medical prognosis Morbidity Patients Percutaneous Coronary Intervention - methods Prognosis Registries Retrospective Studies Rheumatic heart disease Risk Assessment - methods Risk Factors Severity of Illness Index Spain - epidemiology Stents Survival Rate - trends Syntax Time Factors Transcatheter Aortic Valve Replacement - methods Transplants & implants Variables |
| title | Impact of Coronary Revascularization in Patients Who Underwent Transcatheter Aortic Valve Implantation |
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