Overexpression of miRNA-143 Inhibits Colon Cancer Cell Proliferation by Inhibiting Glucose Uptake

MiRNA-143 overexpression is related to upregulated blood glucose level in diabetic mice, and downregulated miRNA-143 has been observed in several types of cancers, indicating its role as a tumor suppression miRNA. Glucose metabolism plays pivotal roles in tumor growth. Therefore, miRNA-143 may targe...

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Veröffentlicht in:	Archives of medical research 2018-10, Vol.49 (7), p.497-503
Hauptverfasser:	Zhao, Jian, Chen, Yuze, Liu, Fang, Yin, Mingdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Blood Glucose - analysis Cell Line, Tumor Cell Proliferation - genetics Colon cancer Colonic Neoplasms - genetics Colonic Neoplasms - pathology Down-Regulation Female Glucose - metabolism Glucose transporter 1 Glucose Transporter Type 1 - biosynthesis Glucose uptake Humans Male MicroRNAs - biosynthesis MicroRNAs - genetics Middle Aged miRNA-143 Signal Transduction Up-Regulation
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