Altered DNA methylation and transcription of WNT2 and DKK1 genes in placentas associated with early-onset preeclampsia

The purpose of this study was to characterize the changes in DNA methylation and transcription of WNT2 and DKK1 genes in placentas associated with early-onset preeclampsia. The study includes three groups: patients with early-onset preeclampsia, normotensive preterm and term births. Placental tissue...

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Veröffentlicht in:	Clinica chimica acta 2019-03, Vol.490, p.154-160
Hauptverfasser:	Zhang, Linlin, Leng, Maodong, Li, Yingying, Yuan, Yang, Yang, Bo, Li, Ying, Yuan, Erfeng, Shi, Wenli, Yan, Shujun, Cui, Shihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult DKK1 DNA Methylation Female Humans Intercellular Signaling Peptides and Proteins - genetics Placenta - metabolism Pre-Eclampsia - genetics Preeclampsia Pregnancy Pyrosequencing RNA, Messenger - genetics RNA, Messenger - metabolism Transcription, Genetic WNT2 Wnt2 Protein - genetics
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