Administration of Fenofibrate Markedly Elevates Fabp3 in Rat Liver and Plasma and Confounds Its Use as a Preclinical Biomarker of Cardiac and Muscle Toxicity

Proteins involved in lipid homeostasis are often regulated through the nuclear peroxisome proliferator‐activated receptors (PPAR). PPARα is the target for the fibrate‐class of drugs. Fenofibrate has been approved for its lipid‐lowering effects in patients with hypercholesterolemia and hypertriglycer...

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Veröffentlicht in:	Lipids 2018-10, Vol.53 (10), p.947-960
Hauptverfasser:	Kochansky, Christopher J., Lyman, Michael J., Fauty, Scott E., Vlasakova, Katerina, D'mello, Anil P.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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