Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit
Objectives To compare patient outcomes using the Pediatric Index of Mortality-3 (PIM-3) model with PIM-2 model for children admitted to the intensive care unit. Methods We prospectively recorded the baseline characteristics, variables of PIM-3 and PIM-2 at admission, and outcomes of children ≤17 yea...
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| Veröffentlicht in: | Indian pediatrics 2018-11, Vol.55 (11), p.972-974 |
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| container_title | Indian pediatrics |
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| creator | Sankar, Jhuma Gulla, Krishna Mohan Kumar, U Vijaya Lodha, Rakesh Kabra, SK |
| description | Objectives
To compare patient outcomes using the Pediatric Index of Mortality-3 (PIM-3) model with PIM-2 model for children admitted to the intensive care unit.
Methods
We prospectively recorded the baseline characteristics, variables of PIM-3 and PIM-2 at admission, and outcomes of children ≤17 years over a period of 11 months. We used Area Under Receiver Operating Characteristics (AU-ROC) curves and Goodness-of-fit (GOF) tests to determine which of the two models had better discrimination and calibration.
Results
Out of 202 children enrolled, 69 (34%) died. Sepsis and pneumonia were the common admitting diagnoses. The AU-ROC was better for PIM-3 (0.75) as compared to PIM-2 (0.69;
P
=0.001). The GOF-P value was 0.001 for both models, that indicated poor calibration of both (
P |
| doi_str_mv | 10.1007/s13312-018-1421-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2161066057</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2161066057</sourcerecordid><originalsourceid>FETCH-LOGICAL-c344t-6f9698f32eca7054195ed8cc7bc0b35600b22b935addda0ff4ad115b107c2a793</originalsourceid><addsrcrecordid>eNp9kLFuFDEQhi0EIiHhAWiQy6QwzNhr-7ZEJwInJUqKpLa8tjdytGsf9i4ib49PF5BoqGak-f5fmo-QDwifEEB_rigEcga4YdhxZPwVOYVed0xL2b9uO2DPFCg8Ie9qfQLggkt8S04EyI1WnTol6zbPe1tizYnmkd6ui8tzqHStMT3Su-CjXUp0dJd8-HUgbnJZ7BSXZ3pxt7u5ZILa5GlbGW83H6ZKY6L2n-gSUo0_A93aEuhDiss5eTPaqYb3L_OMPFx9vd9-Z9e333bbL9fMia5bmBp71W9GwYOzGmSHvQx-45weHAxCKoCB86EX0nrvLYxjZz2iHBC041b34oxcHHv3Jf9YQ13MHKsL02RTyGs1HBWCUiB1Q_GIupJrLWE0-xJnW54NgjnYNkfbptk2B9uGt8zHl_p1mIP_m_ijtwH8CNR2So-hmKe8ltRe_k_rb-L0iO0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2161066057</pqid></control><display><type>article</type><title>Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit</title><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><source>SpringerLink Journals - AutoHoldings</source><creator>Sankar, Jhuma ; Gulla, Krishna Mohan ; Kumar, U Vijaya ; Lodha, Rakesh ; Kabra, SK</creator><creatorcontrib>Sankar, Jhuma ; Gulla, Krishna Mohan ; Kumar, U Vijaya ; Lodha, Rakesh ; Kabra, SK</creatorcontrib><description>Objectives
To compare patient outcomes using the Pediatric Index of Mortality-3 (PIM-3) model with PIM-2 model for children admitted to the intensive care unit.
Methods
We prospectively recorded the baseline characteristics, variables of PIM-3 and PIM-2 at admission, and outcomes of children ≤17 years over a period of 11 months. We used Area Under Receiver Operating Characteristics (AU-ROC) curves and Goodness-of-fit (GOF) tests to determine which of the two models had better discrimination and calibration.
Results
Out of 202 children enrolled, 69 (34%) died. Sepsis and pneumonia were the common admitting diagnoses. The AU-ROC was better for PIM-3 (0.75) as compared to PIM-2 (0.69;
P
=0.001). The GOF-P value was 0.001 for both models, that indicated poor calibration of both (
P
<0.001). The AU-ROC curves were acceptable across different age and diagnostic sub-groups.
Conclusion
PIM-3 had better discrimination when compared to PIM-2 in our unit. Both models had poor calibration across deciles of risk.</description><identifier>ISSN: 0019-6061</identifier><identifier>EISSN: 0974-7559</identifier><identifier>DOI: 10.1007/s13312-018-1421-2</identifier><identifier>PMID: 30587646</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Maternal and Child Health ; Medicine ; Medicine & Public Health ; Pediatric Surgery ; Pediatrics ; Research Paper</subject><ispartof>Indian pediatrics, 2018-11, Vol.55 (11), p.972-974</ispartof><rights>Indian Academy of Pediatrics 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-6f9698f32eca7054195ed8cc7bc0b35600b22b935addda0ff4ad115b107c2a793</citedby><cites>FETCH-LOGICAL-c344t-6f9698f32eca7054195ed8cc7bc0b35600b22b935addda0ff4ad115b107c2a793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s13312-018-1421-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s13312-018-1421-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30587646$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sankar, Jhuma</creatorcontrib><creatorcontrib>Gulla, Krishna Mohan</creatorcontrib><creatorcontrib>Kumar, U Vijaya</creatorcontrib><creatorcontrib>Lodha, Rakesh</creatorcontrib><creatorcontrib>Kabra, SK</creatorcontrib><title>Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit</title><title>Indian pediatrics</title><addtitle>Indian Pediatr</addtitle><addtitle>Indian Pediatr</addtitle><description>Objectives
To compare patient outcomes using the Pediatric Index of Mortality-3 (PIM-3) model with PIM-2 model for children admitted to the intensive care unit.
Methods
We prospectively recorded the baseline characteristics, variables of PIM-3 and PIM-2 at admission, and outcomes of children ≤17 years over a period of 11 months. We used Area Under Receiver Operating Characteristics (AU-ROC) curves and Goodness-of-fit (GOF) tests to determine which of the two models had better discrimination and calibration.
Results
Out of 202 children enrolled, 69 (34%) died. Sepsis and pneumonia were the common admitting diagnoses. The AU-ROC was better for PIM-3 (0.75) as compared to PIM-2 (0.69;
P
=0.001). The GOF-P value was 0.001 for both models, that indicated poor calibration of both (
P
<0.001). The AU-ROC curves were acceptable across different age and diagnostic sub-groups.
Conclusion
PIM-3 had better discrimination when compared to PIM-2 in our unit. Both models had poor calibration across deciles of risk.</description><subject>Maternal and Child Health</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Research Paper</subject><issn>0019-6061</issn><issn>0974-7559</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kLFuFDEQhi0EIiHhAWiQy6QwzNhr-7ZEJwInJUqKpLa8tjdytGsf9i4ib49PF5BoqGak-f5fmo-QDwifEEB_rigEcga4YdhxZPwVOYVed0xL2b9uO2DPFCg8Ie9qfQLggkt8S04EyI1WnTol6zbPe1tizYnmkd6ui8tzqHStMT3Su-CjXUp0dJd8-HUgbnJZ7BSXZ3pxt7u5ZILa5GlbGW83H6ZKY6L2n-gSUo0_A93aEuhDiss5eTPaqYb3L_OMPFx9vd9-Z9e333bbL9fMia5bmBp71W9GwYOzGmSHvQx-45weHAxCKoCB86EX0nrvLYxjZz2iHBC041b34oxcHHv3Jf9YQ13MHKsL02RTyGs1HBWCUiB1Q_GIupJrLWE0-xJnW54NgjnYNkfbptk2B9uGt8zHl_p1mIP_m_ijtwH8CNR2So-hmKe8ltRe_k_rb-L0iO0</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Sankar, Jhuma</creator><creator>Gulla, Krishna Mohan</creator><creator>Kumar, U Vijaya</creator><creator>Lodha, Rakesh</creator><creator>Kabra, SK</creator><general>Springer India</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20181101</creationdate><title>Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit</title><author>Sankar, Jhuma ; Gulla, Krishna Mohan ; Kumar, U Vijaya ; Lodha, Rakesh ; Kabra, SK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-6f9698f32eca7054195ed8cc7bc0b35600b22b935addda0ff4ad115b107c2a793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Maternal and Child Health</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Pediatric Surgery</topic><topic>Pediatrics</topic><topic>Research Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sankar, Jhuma</creatorcontrib><creatorcontrib>Gulla, Krishna Mohan</creatorcontrib><creatorcontrib>Kumar, U Vijaya</creatorcontrib><creatorcontrib>Lodha, Rakesh</creatorcontrib><creatorcontrib>Kabra, SK</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Indian pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sankar, Jhuma</au><au>Gulla, Krishna Mohan</au><au>Kumar, U Vijaya</au><au>Lodha, Rakesh</au><au>Kabra, SK</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit</atitle><jtitle>Indian pediatrics</jtitle><stitle>Indian Pediatr</stitle><addtitle>Indian Pediatr</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>55</volume><issue>11</issue><spage>972</spage><epage>974</epage><pages>972-974</pages><issn>0019-6061</issn><eissn>0974-7559</eissn><abstract>Objectives
To compare patient outcomes using the Pediatric Index of Mortality-3 (PIM-3) model with PIM-2 model for children admitted to the intensive care unit.
Methods
We prospectively recorded the baseline characteristics, variables of PIM-3 and PIM-2 at admission, and outcomes of children ≤17 years over a period of 11 months. We used Area Under Receiver Operating Characteristics (AU-ROC) curves and Goodness-of-fit (GOF) tests to determine which of the two models had better discrimination and calibration.
Results
Out of 202 children enrolled, 69 (34%) died. Sepsis and pneumonia were the common admitting diagnoses. The AU-ROC was better for PIM-3 (0.75) as compared to PIM-2 (0.69;
P
=0.001). The GOF-P value was 0.001 for both models, that indicated poor calibration of both (
P
<0.001). The AU-ROC curves were acceptable across different age and diagnostic sub-groups.
Conclusion
PIM-3 had better discrimination when compared to PIM-2 in our unit. Both models had poor calibration across deciles of risk.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>30587646</pmid><doi>10.1007/s13312-018-1421-2</doi><tpages>3</tpages></addata></record> |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; SpringerLink Journals - AutoHoldings |
| subjects | Maternal and Child Health Medicine Medicine & Public Health Pediatric Surgery Pediatrics Research Paper |
| title | Comparison of Outcomes using Pediatric Index of Mortality (PIM)-3 and PIM-2 Models in a Pediatric Intensive Care Unit |
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