Quercetin sensitizes human myeloid leukemia KG‐1 cells against TRAIL‐induced apoptosis

Introduction Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Conventional treatments are associated with cytotoxicity and systemic side effects. Hence, efforts in the field of cancer treatment are focused on finding the strategies which can specifically target the tumor cel...

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Veröffentlicht in:	Journal of cellular physiology 2019-08, Vol.234 (8), p.13233-13241
Hauptverfasser:	Naimi, Adel, Entezari, Atefeh, Hagh, Majid Farshdousti, Hassanzadeh, Ali, Saraei, Raedeh, Solali, Saeed
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia acute myeloid leukemia (AML) Adults Annexin V Antineoplastic Combined Chemotherapy Protocols - pharmacology Apoptosis Apoptosis - drug effects Cancer Cell Line, Tumor Cytotoxicity Drug Synergism Gene expression Genes Humans Iodides Leukemia Leukemia, Myeloid, Acute - pathology Myeloid leukemia Propidium iodide Proteins Quercetin quercetin (QUR) Quercetin - pharmacology Ribonucleic acid RNA Sensitizing Side effects TNF-Related Apoptosis-Inducing Ligand - pharmacology TNF‐related apoptosis‐inducing ligand (TRAIL) Toxicity TRAIL protein Tumor cells Tumor necrosis factor
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