Standardized nursing and therapeutic effect of oxycontin on oral mucosal pain in nasopharyngeal carcinoma patients
Aim: This study aims to explore the standardized nursing and therapeutic effect of OxyContin on oral mucosal pain in nasopharyngeal carcinoma (NPC) patients with concurrent chemoradiotherapy. Materials and Methods: From March 2016 to December 2017, 60 patients with NPC were selected from the Sun Yat...
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Veröffentlicht in: | Journal of cancer research and therapeutics 2018-01, Vol.14 (7), p.1594-1599 |
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description | Aim: This study aims to explore the standardized nursing and therapeutic effect of OxyContin on oral mucosal pain in nasopharyngeal carcinoma (NPC) patients with concurrent chemoradiotherapy.
Materials and Methods: From March 2016 to December 2017, 60 patients with NPC were selected from the Sun Yat-Sen University Cancer Center. Patients consuming OxyContin for moderate and severe pain were divided into the experimental group and control group, respectively. All the patients were given OxyContin 10 mg orally, and the dose was adjusted according to the degree of pain relief until it was significantly relieved. At the same time, the combination of analgesic drugs with standardized nursing intervention for pain was granted, and the analgesic effect, adverse effects, and quality of life of both groups were analyzed.
Results: There was no significant difference between the total dose of radiotherapy and OxyContin. OxyContin could significantly improve the quality of life in patients with moderate pain (P < 0.05), while the effect was not significant in patients with severe pain.
Conclusion: Patients with NPC having oral mucosal pain after radiotherapy and chemotherapy need intervention at the earliest. The application of OxyContin and cancer pain standardized nursing care can improve the analgesic efficacy, reduce drug adverse effects, and improve the patient's quality of life. |
doi_str_mv | 10.4103/jcrt.JCRT_551_18 |
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Materials and Methods: From March 2016 to December 2017, 60 patients with NPC were selected from the Sun Yat-Sen University Cancer Center. Patients consuming OxyContin for moderate and severe pain were divided into the experimental group and control group, respectively. All the patients were given OxyContin 10 mg orally, and the dose was adjusted according to the degree of pain relief until it was significantly relieved. At the same time, the combination of analgesic drugs with standardized nursing intervention for pain was granted, and the analgesic effect, adverse effects, and quality of life of both groups were analyzed.
Results: There was no significant difference between the total dose of radiotherapy and OxyContin. OxyContin could significantly improve the quality of life in patients with moderate pain (P < 0.05), while the effect was not significant in patients with severe pain.
Conclusion: Patients with NPC having oral mucosal pain after radiotherapy and chemotherapy need intervention at the earliest. The application of OxyContin and cancer pain standardized nursing care can improve the analgesic efficacy, reduce drug adverse effects, and improve the patient's quality of life.</description><identifier>ISSN: 0973-1482</identifier><identifier>EISSN: 1998-4138</identifier><identifier>DOI: 10.4103/jcrt.JCRT_551_18</identifier><identifier>PMID: 30589045</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Adult ; Aged ; Analgesics ; Analgesics, Opioid - administration & dosage ; Cancer Pain - diagnosis ; Cancer Pain - etiology ; Cancer Pain - therapy ; Cancer therapies ; Chemotherapy ; Education ; Epidemics ; Female ; Humans ; Male ; Middle Aged ; Mouth Mucosa - drug effects ; Mouth Mucosa - physiopathology ; Nasopharyngeal Carcinoma - complications ; Nurses ; Nursing ; Nursing Care ; Oxycodone - administration & dosage ; Pain ; Pain Management ; Pain Measurement ; Patient Compliance ; Patients ; Psychotherapy ; Quality of Life ; Radiation therapy ; Sleep ; Throat cancer ; Weight Loss ; Young Adult</subject><ispartof>Journal of cancer research and therapeutics, 2018-01, Vol.14 (7), p.1594-1599</ispartof><rights>2018. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c429d-36363b10529f9a8ed7ee385a81ddb05470503b8ea55648437a7a4228fd8213c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27458,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30589045$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hu, Wen</creatorcontrib><creatorcontrib>Chen, Linmin</creatorcontrib><creatorcontrib>Wang, Cong</creatorcontrib><creatorcontrib>Guo, Ling</creatorcontrib><creatorcontrib>Hua, Xin</creatorcontrib><creatorcontrib>Cai, Yucong</creatorcontrib><creatorcontrib>Fan, Yuying</creatorcontrib><title>Standardized nursing and therapeutic effect of oxycontin on oral mucosal pain in nasopharyngeal carcinoma patients</title><title>Journal of cancer research and therapeutics</title><addtitle>J Cancer Res Ther</addtitle><description>Aim: This study aims to explore the standardized nursing and therapeutic effect of OxyContin on oral mucosal pain in nasopharyngeal carcinoma (NPC) patients with concurrent chemoradiotherapy.
Materials and Methods: From March 2016 to December 2017, 60 patients with NPC were selected from the Sun Yat-Sen University Cancer Center. Patients consuming OxyContin for moderate and severe pain were divided into the experimental group and control group, respectively. All the patients were given OxyContin 10 mg orally, and the dose was adjusted according to the degree of pain relief until it was significantly relieved. At the same time, the combination of analgesic drugs with standardized nursing intervention for pain was granted, and the analgesic effect, adverse effects, and quality of life of both groups were analyzed.
Results: There was no significant difference between the total dose of radiotherapy and OxyContin. OxyContin could significantly improve the quality of life in patients with moderate pain (P < 0.05), while the effect was not significant in patients with severe pain.
Conclusion: Patients with NPC having oral mucosal pain after radiotherapy and chemotherapy need intervention at the earliest. The application of OxyContin and cancer pain standardized nursing care can improve the analgesic efficacy, reduce drug adverse effects, and improve the patient's quality of life.</description><subject>Adult</subject><subject>Aged</subject><subject>Analgesics</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Cancer Pain - diagnosis</subject><subject>Cancer Pain - etiology</subject><subject>Cancer Pain - therapy</subject><subject>Cancer therapies</subject><subject>Chemotherapy</subject><subject>Education</subject><subject>Epidemics</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mouth Mucosa - drug effects</subject><subject>Mouth Mucosa - physiopathology</subject><subject>Nasopharyngeal Carcinoma - complications</subject><subject>Nurses</subject><subject>Nursing</subject><subject>Nursing Care</subject><subject>Oxycodone - administration & dosage</subject><subject>Pain</subject><subject>Pain Management</subject><subject>Pain Measurement</subject><subject>Patient Compliance</subject><subject>Patients</subject><subject>Psychotherapy</subject><subject>Quality of Life</subject><subject>Radiation therapy</subject><subject>Sleep</subject><subject>Throat cancer</subject><subject>Weight Loss</subject><subject>Young Adult</subject><issn>0973-1482</issn><issn>1998-4138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kUFr3DAQhUVoabbb3nMqhl5ycSJZki0fy9K0CYFAu3ehlcaJN7bkSjLb9Ndnlk1CCQQNDDy-mdHMI-SE0TPBKD_f2pjPrla_1lpKppk6IgvWtqoUjKt3ZEHbhpdMqOqYfExpS6lsqkp9IMecStVSIRck_s7GOxNd_w9c4eeYen9boFTkO4hmgjn3toCuA5uL0BXh74MNPve-CBjRDMU425AwTwZFDG9SmO5MfPC3gLI10fY-jAaB3IPP6RN535khweenvCTri-_r1c_y-ubH5erbdWlF1bqS1_g2jMqq7VqjwDUAXEmjmHMbKkVDJeUbBUbKWijBG9MYget1TlWMW74kp4e2Uwx_ZkhZj32yMAzGQ5iTrljNKM7AOy7J11foNszR4-f2FK2VEqpGih4oG0NKETo9xX7ERTWjem-H3tuh_7MDS748NZ43I7iXguf7I7A6ALswZIjpfph3EDWy9z7s3mysmWyFfraOPwJDx5-0</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Hu, Wen</creator><creator>Chen, Linmin</creator><creator>Wang, Cong</creator><creator>Guo, Ling</creator><creator>Hua, Xin</creator><creator>Cai, Yucong</creator><creator>Fan, Yuying</creator><general>Wolters Kluwer India Pvt. 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Fan, Yuying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c429d-36363b10529f9a8ed7ee385a81ddb05470503b8ea55648437a7a4228fd8213c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Analgesics</topic><topic>Analgesics, Opioid - administration & dosage</topic><topic>Cancer Pain - diagnosis</topic><topic>Cancer Pain - etiology</topic><topic>Cancer Pain - therapy</topic><topic>Cancer therapies</topic><topic>Chemotherapy</topic><topic>Education</topic><topic>Epidemics</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mouth Mucosa - drug effects</topic><topic>Mouth Mucosa - physiopathology</topic><topic>Nasopharyngeal Carcinoma - complications</topic><topic>Nurses</topic><topic>Nursing</topic><topic>Nursing Care</topic><topic>Oxycodone - administration & dosage</topic><topic>Pain</topic><topic>Pain Management</topic><topic>Pain Measurement</topic><topic>Patient Compliance</topic><topic>Patients</topic><topic>Psychotherapy</topic><topic>Quality of Life</topic><topic>Radiation therapy</topic><topic>Sleep</topic><topic>Throat cancer</topic><topic>Weight Loss</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hu, Wen</creatorcontrib><creatorcontrib>Chen, Linmin</creatorcontrib><creatorcontrib>Wang, Cong</creatorcontrib><creatorcontrib>Guo, Ling</creatorcontrib><creatorcontrib>Hua, Xin</creatorcontrib><creatorcontrib>Cai, Yucong</creatorcontrib><creatorcontrib>Fan, Yuying</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cancer research and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hu, Wen</au><au>Chen, Linmin</au><au>Wang, Cong</au><au>Guo, Ling</au><au>Hua, Xin</au><au>Cai, Yucong</au><au>Fan, Yuying</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Standardized nursing and therapeutic effect of oxycontin on oral mucosal pain in nasopharyngeal carcinoma patients</atitle><jtitle>Journal of cancer research and therapeutics</jtitle><addtitle>J Cancer Res Ther</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>14</volume><issue>7</issue><spage>1594</spage><epage>1599</epage><pages>1594-1599</pages><issn>0973-1482</issn><eissn>1998-4138</eissn><abstract>Aim: This study aims to explore the standardized nursing and therapeutic effect of OxyContin on oral mucosal pain in nasopharyngeal carcinoma (NPC) patients with concurrent chemoradiotherapy.
Materials and Methods: From March 2016 to December 2017, 60 patients with NPC were selected from the Sun Yat-Sen University Cancer Center. Patients consuming OxyContin for moderate and severe pain were divided into the experimental group and control group, respectively. All the patients were given OxyContin 10 mg orally, and the dose was adjusted according to the degree of pain relief until it was significantly relieved. At the same time, the combination of analgesic drugs with standardized nursing intervention for pain was granted, and the analgesic effect, adverse effects, and quality of life of both groups were analyzed.
Results: There was no significant difference between the total dose of radiotherapy and OxyContin. OxyContin could significantly improve the quality of life in patients with moderate pain (P < 0.05), while the effect was not significant in patients with severe pain.
Conclusion: Patients with NPC having oral mucosal pain after radiotherapy and chemotherapy need intervention at the earliest. The application of OxyContin and cancer pain standardized nursing care can improve the analgesic efficacy, reduce drug adverse effects, and improve the patient's quality of life.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>30589045</pmid><doi>10.4103/jcrt.JCRT_551_18</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Analgesics Analgesics, Opioid - administration & dosage Cancer Pain - diagnosis Cancer Pain - etiology Cancer Pain - therapy Cancer therapies Chemotherapy Education Epidemics Female Humans Male Middle Aged Mouth Mucosa - drug effects Mouth Mucosa - physiopathology Nasopharyngeal Carcinoma - complications Nurses Nursing Nursing Care Oxycodone - administration & dosage Pain Pain Management Pain Measurement Patient Compliance Patients Psychotherapy Quality of Life Radiation therapy Sleep Throat cancer Weight Loss Young Adult |
title | Standardized nursing and therapeutic effect of oxycontin on oral mucosal pain in nasopharyngeal carcinoma patients |
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