Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope
To test the hypothesis that increased venous compliance manifested as inferior vena cava (IVC) dilation is an important substrate for syncope in children. IVC diameters were measured in 191 children and adolescents with syncope and in 95 controls. Subjects were divided based on age
Gespeichert in:
| Veröffentlicht in: | The Journal of pediatrics 2019-04, Vol.207, p.49-53.e3 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 53.e3 |
|---|---|
| container_issue | |
| container_start_page | 49 |
| container_title | The Journal of pediatrics |
| container_volume | 207 |
| creator | Shivaram, Pushpa Angtuaco, Sylvia Ahmed, Aziez Daily, Joshua Grigsby, Deborah F. Li, Ling Craft, Mary Danford, David Kutty, Shelby |
| description | To test the hypothesis that increased venous compliance manifested as inferior vena cava (IVC) dilation is an important substrate for syncope in children.
IVC diameters were measured in 191 children and adolescents with syncope and in 95 controls. Subjects were divided based on age |
| doi_str_mv | 10.1016/j.jpeds.2018.11.039 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2160152554</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S002234761831686X</els_id><sourcerecordid>2160152554</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-ed44fa702ba48f1f3dfbda679890630cc0751d303e0bb6c1d84e2863b741e80a3</originalsourceid><addsrcrecordid>eNp9kLtOxDAQRS0EguXxBUjIJU3COE6cpKBYLU8JCYlXaxx7sniV2IudBfH3BBYoqaY5d-7MIeSQQcqAiZNFuliiiWkGrEoZS4HXG2TCoC4TUXG-SSYAWZbwvBQ7ZDfGBQDUOcA22eFQVCMnJuR5OsfkDjs1oKGzF-XmGKl19Nq1GKwP9AmdojP1puiZ7dFF612kqvduPuK2MwEdVc7QqfEdRo1uiPTdDi_0_sNpv8R9stWqLuLBz9wjjxfnD7Or5Ob28no2vUk0L-ohQZPnrSoha1Retazlpm2MEmVd1SA4aA1lwQwHjtA0QjNT5ZhVgjdlzrACxffI8XrvMvjXFcZB9nY8p-uUQ7-KMmMCWJEVRT6ifI3q4GMM2MplsL0KH5KB_FIrF_JbrfxSKxmTo9oxdfRTsGp6NH-ZX5cjcLoGcHzzzWKQUVt0Go0NqAdpvP234BMYT4sc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2160152554</pqid></control><display><type>article</type><title>Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Shivaram, Pushpa ; Angtuaco, Sylvia ; Ahmed, Aziez ; Daily, Joshua ; Grigsby, Deborah F. ; Li, Ling ; Craft, Mary ; Danford, David ; Kutty, Shelby</creator><creatorcontrib>Shivaram, Pushpa ; Angtuaco, Sylvia ; Ahmed, Aziez ; Daily, Joshua ; Grigsby, Deborah F. ; Li, Ling ; Craft, Mary ; Danford, David ; Kutty, Shelby</creatorcontrib><description>To test the hypothesis that increased venous compliance manifested as inferior vena cava (IVC) dilation is an important substrate for syncope in children.
IVC diameters were measured in 191 children and adolescents with syncope and in 95 controls. Subjects were divided based on age <12 years (younger group) and ≥12 years (older group). IVC measurements at the right atrial junction (IVC-RA), 10 mm below the IVC-RA junction (IVC-RA10), and at the point of maximal diameter (IVCmax) were made. The linear relation to body surface area (BSA) was confirmed, as were dimensions indexed to BSA (iIVC). Relationships between iIVC and the time of day were evaluated.
In the syncope group, the mean age was 12.9 ± 3.6 years, mean weight was 54.7 ± 23 kg, and mean BSA was 1.5 ± 0.4 m2. Among controls, all IVC dimensions varied linearly with BSA (P < .001). In the older group (140 patients with syncope and 60 controls), all iIVC dimensions were larger in the syncope cohort: iIVC-RA, 9 vs 7.7 mm/m2 (P < .0001); iIVC-RA10, 9.4 vs 8.1 mm/m2 (P < .0001); iIVCmax, 11.7 vs 10.6 mm/m2 (P = .002). In the younger group (51 patients with syncope and 35 controls), there were no differences in iIVC measurements between the syncope cohort and controls: iIVC-RA, 10.2 vs 11.3 mm/m2; iIVC-RA10, 11.7 vs 12.0 mm/m2; iIVCmax, 14.2 vs 14.7 mm/m2 (P > .05 for all).
The IVC is enlarged in teenagers with syncope compared with controls, suggesting that venous capacitance and resultant pooling play roles in the pathogenesis of syncope. In contrast, younger children with syncope do not demonstrate IVC dilation, suggesting that their syncope arises from a different mechanism.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/j.jpeds.2018.11.039</identifier><identifier>PMID: 30580976</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Age Factors ; Case-Control Studies ; Child ; Echocardiography ; Female ; Humans ; inferior vena cava ; Male ; pediatrics ; Retrospective Studies ; syncope ; Syncope - complications ; Syncope - physiopathology ; Vena Cava, Inferior - diagnostic imaging ; Vena Cava, Inferior - pathology</subject><ispartof>The Journal of pediatrics, 2019-04, Vol.207, p.49-53.e3</ispartof><rights>2018 Elsevier Inc.</rights><rights>Copyright © 2018 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-ed44fa702ba48f1f3dfbda679890630cc0751d303e0bb6c1d84e2863b741e80a3</citedby><cites>FETCH-LOGICAL-c359t-ed44fa702ba48f1f3dfbda679890630cc0751d303e0bb6c1d84e2863b741e80a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S002234761831686X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30580976$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shivaram, Pushpa</creatorcontrib><creatorcontrib>Angtuaco, Sylvia</creatorcontrib><creatorcontrib>Ahmed, Aziez</creatorcontrib><creatorcontrib>Daily, Joshua</creatorcontrib><creatorcontrib>Grigsby, Deborah F.</creatorcontrib><creatorcontrib>Li, Ling</creatorcontrib><creatorcontrib>Craft, Mary</creatorcontrib><creatorcontrib>Danford, David</creatorcontrib><creatorcontrib>Kutty, Shelby</creatorcontrib><title>Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>To test the hypothesis that increased venous compliance manifested as inferior vena cava (IVC) dilation is an important substrate for syncope in children.
IVC diameters were measured in 191 children and adolescents with syncope and in 95 controls. Subjects were divided based on age <12 years (younger group) and ≥12 years (older group). IVC measurements at the right atrial junction (IVC-RA), 10 mm below the IVC-RA junction (IVC-RA10), and at the point of maximal diameter (IVCmax) were made. The linear relation to body surface area (BSA) was confirmed, as were dimensions indexed to BSA (iIVC). Relationships between iIVC and the time of day were evaluated.
In the syncope group, the mean age was 12.9 ± 3.6 years, mean weight was 54.7 ± 23 kg, and mean BSA was 1.5 ± 0.4 m2. Among controls, all IVC dimensions varied linearly with BSA (P < .001). In the older group (140 patients with syncope and 60 controls), all iIVC dimensions were larger in the syncope cohort: iIVC-RA, 9 vs 7.7 mm/m2 (P < .0001); iIVC-RA10, 9.4 vs 8.1 mm/m2 (P < .0001); iIVCmax, 11.7 vs 10.6 mm/m2 (P = .002). In the younger group (51 patients with syncope and 35 controls), there were no differences in iIVC measurements between the syncope cohort and controls: iIVC-RA, 10.2 vs 11.3 mm/m2; iIVC-RA10, 11.7 vs 12.0 mm/m2; iIVCmax, 14.2 vs 14.7 mm/m2 (P > .05 for all).
The IVC is enlarged in teenagers with syncope compared with controls, suggesting that venous capacitance and resultant pooling play roles in the pathogenesis of syncope. In contrast, younger children with syncope do not demonstrate IVC dilation, suggesting that their syncope arises from a different mechanism.</description><subject>Adolescent</subject><subject>Age Factors</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Humans</subject><subject>inferior vena cava</subject><subject>Male</subject><subject>pediatrics</subject><subject>Retrospective Studies</subject><subject>syncope</subject><subject>Syncope - complications</subject><subject>Syncope - physiopathology</subject><subject>Vena Cava, Inferior - diagnostic imaging</subject><subject>Vena Cava, Inferior - pathology</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLtOxDAQRS0EguXxBUjIJU3COE6cpKBYLU8JCYlXaxx7sniV2IudBfH3BBYoqaY5d-7MIeSQQcqAiZNFuliiiWkGrEoZS4HXG2TCoC4TUXG-SSYAWZbwvBQ7ZDfGBQDUOcA22eFQVCMnJuR5OsfkDjs1oKGzF-XmGKl19Nq1GKwP9AmdojP1puiZ7dFF612kqvduPuK2MwEdVc7QqfEdRo1uiPTdDi_0_sNpv8R9stWqLuLBz9wjjxfnD7Or5Ob28no2vUk0L-ohQZPnrSoha1Retazlpm2MEmVd1SA4aA1lwQwHjtA0QjNT5ZhVgjdlzrACxffI8XrvMvjXFcZB9nY8p-uUQ7-KMmMCWJEVRT6ifI3q4GMM2MplsL0KH5KB_FIrF_JbrfxSKxmTo9oxdfRTsGp6NH-ZX5cjcLoGcHzzzWKQUVt0Go0NqAdpvP234BMYT4sc</recordid><startdate>201904</startdate><enddate>201904</enddate><creator>Shivaram, Pushpa</creator><creator>Angtuaco, Sylvia</creator><creator>Ahmed, Aziez</creator><creator>Daily, Joshua</creator><creator>Grigsby, Deborah F.</creator><creator>Li, Ling</creator><creator>Craft, Mary</creator><creator>Danford, David</creator><creator>Kutty, Shelby</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201904</creationdate><title>Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope</title><author>Shivaram, Pushpa ; Angtuaco, Sylvia ; Ahmed, Aziez ; Daily, Joshua ; Grigsby, Deborah F. ; Li, Ling ; Craft, Mary ; Danford, David ; Kutty, Shelby</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-ed44fa702ba48f1f3dfbda679890630cc0751d303e0bb6c1d84e2863b741e80a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Age Factors</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Humans</topic><topic>inferior vena cava</topic><topic>Male</topic><topic>pediatrics</topic><topic>Retrospective Studies</topic><topic>syncope</topic><topic>Syncope - complications</topic><topic>Syncope - physiopathology</topic><topic>Vena Cava, Inferior - diagnostic imaging</topic><topic>Vena Cava, Inferior - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shivaram, Pushpa</creatorcontrib><creatorcontrib>Angtuaco, Sylvia</creatorcontrib><creatorcontrib>Ahmed, Aziez</creatorcontrib><creatorcontrib>Daily, Joshua</creatorcontrib><creatorcontrib>Grigsby, Deborah F.</creatorcontrib><creatorcontrib>Li, Ling</creatorcontrib><creatorcontrib>Craft, Mary</creatorcontrib><creatorcontrib>Danford, David</creatorcontrib><creatorcontrib>Kutty, Shelby</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shivaram, Pushpa</au><au>Angtuaco, Sylvia</au><au>Ahmed, Aziez</au><au>Daily, Joshua</au><au>Grigsby, Deborah F.</au><au>Li, Ling</au><au>Craft, Mary</au><au>Danford, David</au><au>Kutty, Shelby</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2019-04</date><risdate>2019</risdate><volume>207</volume><spage>49</spage><epage>53.e3</epage><pages>49-53.e3</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>To test the hypothesis that increased venous compliance manifested as inferior vena cava (IVC) dilation is an important substrate for syncope in children.
IVC diameters were measured in 191 children and adolescents with syncope and in 95 controls. Subjects were divided based on age <12 years (younger group) and ≥12 years (older group). IVC measurements at the right atrial junction (IVC-RA), 10 mm below the IVC-RA junction (IVC-RA10), and at the point of maximal diameter (IVCmax) were made. The linear relation to body surface area (BSA) was confirmed, as were dimensions indexed to BSA (iIVC). Relationships between iIVC and the time of day were evaluated.
In the syncope group, the mean age was 12.9 ± 3.6 years, mean weight was 54.7 ± 23 kg, and mean BSA was 1.5 ± 0.4 m2. Among controls, all IVC dimensions varied linearly with BSA (P < .001). In the older group (140 patients with syncope and 60 controls), all iIVC dimensions were larger in the syncope cohort: iIVC-RA, 9 vs 7.7 mm/m2 (P < .0001); iIVC-RA10, 9.4 vs 8.1 mm/m2 (P < .0001); iIVCmax, 11.7 vs 10.6 mm/m2 (P = .002). In the younger group (51 patients with syncope and 35 controls), there were no differences in iIVC measurements between the syncope cohort and controls: iIVC-RA, 10.2 vs 11.3 mm/m2; iIVC-RA10, 11.7 vs 12.0 mm/m2; iIVCmax, 14.2 vs 14.7 mm/m2 (P > .05 for all).
The IVC is enlarged in teenagers with syncope compared with controls, suggesting that venous capacitance and resultant pooling play roles in the pathogenesis of syncope. In contrast, younger children with syncope do not demonstrate IVC dilation, suggesting that their syncope arises from a different mechanism.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30580976</pmid><doi>10.1016/j.jpeds.2018.11.039</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3476 |
| ispartof | The Journal of pediatrics, 2019-04, Vol.207, p.49-53.e3 |
| issn | 0022-3476 1097-6833 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2160152554 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Age Factors Case-Control Studies Child Echocardiography Female Humans inferior vena cava Male pediatrics Retrospective Studies syncope Syncope - complications Syncope - physiopathology Vena Cava, Inferior - diagnostic imaging Vena Cava, Inferior - pathology |
| title | Age-Related Changes in Inferior Vena Cava Dimensions among Children and Adolescents with Syncope |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T15%3A00%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Age-Related%20Changes%20in%20Inferior%20Vena%20Cava%20Dimensions%20among%20Children%20and%20Adolescents%20with%20Syncope&rft.jtitle=The%20Journal%20of%20pediatrics&rft.au=Shivaram,%20Pushpa&rft.date=2019-04&rft.volume=207&rft.spage=49&rft.epage=53.e3&rft.pages=49-53.e3&rft.issn=0022-3476&rft.eissn=1097-6833&rft_id=info:doi/10.1016/j.jpeds.2018.11.039&rft_dat=%3Cproquest_cross%3E2160152554%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2160152554&rft_id=info:pmid/30580976&rft_els_id=S002234761831686X&rfr_iscdi=true |