Unc-51 like autophagy activating kinase 1 accelerates angiotensin II-induced cardiac hypertrophy through promoting oxidative stress regulated by Nrf-2/HO-1 pathway

Unc-51 like autophagy activating kinase 1 (ULK1) is a serine/threonine kinase and the mammalian functional homolog of yeast Atg1, and plays an essential role in regulating various cellular processes. However, whether ULK1 can influence cardiac hypertrophy is unclear. In the study, we investigated th...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-01, Vol.509 (1), p.32-39
Hauptverfasser:	Zhang, Anji, Wang, Meixue, Zhuo, Pengzhan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac hypertrophy Inflammation and fibrosis Nrf-2/HO-1 ROS ULK1
Online-Zugang:	Volltext
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