Bioassay-guided isolation of cytotoxic compounds from Chrysophthalmum montanum (DC.) Boiss

Bioassay-guided isolation of the 80% methanol extract of the aerial parts of Chrysophthalmum montanum (DC.) Boiss. (Asteraceae) led to the isolation of four known guaianolide-type sesquiterpene lactones, 6α-acetoxy-4α-hydroxy-1βH-guaia-9.11(13)-dien-12.8α-olide (1), 6α-acetoxy-4α-hydroxy-9β.10β-epox...

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Veröffentlicht in:	Food and chemical toxicology 2019-03, Vol.125, p.10-20
Hauptverfasser:	Ayaz, Fatma, Küçükboyacı, Nurgün, Gören, Nezhun, Çalış, İhsan, Aydınlık, Şeyma, Ulukaya, Engin, Duman, Hayri, Choudhary, Muhammad Iqbal
Format:	Artikel
Sprache:	eng
Schlagworte:	Asteraceae Chrysophthalmum montanum Cytotoxicity HT-29 colon cancer cell line Sesquiterpene lactones Steroidal glycosides
Online-Zugang:	Volltext
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