Synthesis of D‑Ring Annulated Pyridosteroids from β‑Formyl Enamides and Their Biological Evaluations

Herein, we report the synthesis of a novel class of substituted androst­[17,16-b]­pyridines (pyridosteroids) from the reaction of β-formyl enamides with alkynes in high yields. The optimized reaction protocol was extended to acyclic and cyclic β-formyl enamides to afford nonsteroidal pyridines. Cell...

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Veröffentlicht in:	ACS combinatorial science 2019-01, Vol.21 (1), p.11-27
Hauptverfasser:	Nongthombam, Geetmani Singh, Borah, Kasmika, Muinao, Thingreila, Silla, Yumnam, Pal, Mintu, Deka Boruah, Hari Prasanna, Boruah, Romesh Chandra
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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