Prenatal thyroxine treatment promotes anxiolysis in male Swiss mice offspring

The proper functioning of the maternal thyroid plays a crucial role in fetal development. Thus, the aim of our study was to verify how maternal hyperthyroidism is able to change behavioral parameters in mice offspring during adulthood. For this purpose, pregnant Swiss mice (n = 24 and ~35 g) were ra...

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Veröffentlicht in:	Hormones and behavior 2019-02, Vol.108, p.10-19
Hauptverfasser:	Laureano-Melo, Roberto, Souza, Janaina Sena de, da Conceição, Rodrigo Rodrigues, Albuquerque, Josie Marcelle Lira, Rodrigues, Nayana Coutinho, Marinho, Bruno Guimarães, Olivares, Emerson Lopes, Giannocco, Gisele, Côrtes, Wellington da Silva
Format:	Artikel
Sprache:	eng
Schlagworte:	Affect - drug effects Animals Anti-Anxiety Agents - blood Anti-Anxiety Agents - pharmacology Anxiety Anxiety - pathology Anxiety - prevention & control Anxiety - psychology Female GABAergic system Hippocampus - drug effects Hippocampus - metabolism Hyperthyroidism - pathology Hyperthyroidism - psychology Male Maze Learning Mice Offspring Pregnancy Prenatal Exposure Delayed Effects - metabolism Prenatal Exposure Delayed Effects - psychology Serotonergic system Thyroxine Thyroxine - blood Thyroxine - pharmacology
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