GM-CSF Administration Improves Defects in Innate Immunity and Sepsis Survival in Obese Diabetic Mice

Sepsis is the leading cause of death in the intensive care unit with an overall mortality rate of 20%. Individuals who are obese and have type 2 diabetes have increased recurrent, chronic, nosocomial infections that worsen the long-term morbidity and mortality from sepsis. Additionally, animal model...

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Veröffentlicht in:	The Journal of immunology (1950) 2019-02, Vol.202 (3), p.931-942
Hauptverfasser:	Frydrych, Lynn M, Bian, Guowu, Fattahi, Fatemeh, Morris, Susan B, O'Rourke, Robert W, Lumeng, Carey N, Kunkel, Steven L, Ward, Peter A, Delano, Matthew J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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