Total Synthesis in Search of Potent Antibody–Drug Conjugate Payloads. From the Fundamentals to the Translational

Conspectus The emergence and evolution of antibody–drug conjugates (ADCs) as targeted cancer therapies in recent years is a living example of the “magic bullet” concept of Paul Ehrlich, introduced by him more than a century ago. Consisting of three components, the antibody serving as the delivery sy...

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Veröffentlicht in:	Accounts of chemical research 2019-01, Vol.52 (1), p.127-139
Hauptverfasser:	Nicolaou, Kyriacos C, Rigol, Stephan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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