Hepatic microcirculation and mechanisms of portal hypertension

The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in liver homeostasis, including in preserving hepatocyte function, regulating the vascular tone and controlling inflammation....

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Veröffentlicht in:	Nature reviews. Gastroenterology & hepatology 2019-04, Vol.16 (4), p.221-234
Hauptverfasser:	Gracia-Sancho, Jordi, Marrone, Giusi, Fernández-Iglesias, Anabel
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/1338 631/443/1338/1872 692/4020/4021/288/2140 692/699/1503/1607/1604 Animal models Bile Biomedicine Care and treatment Cirrhosis Development and progression Endothelial cells Epidemiology Gastroenterology Health aspects Hepatocytes Hepatology Homeostasis Hypertension Liver diseases Macrophages Medicine Medicine & Public Health Microcirculation Microvasculature Morbidity Phenotypes Portal hypertension Review Article Signal transduction Stellate cells Therapeutic applications
Online-Zugang:	Volltext
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