CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation

Figure. Mechanism of CP-25 combined with MTX/LEF to ameliorate AA rats In the one hand, CP-25 alone and in combination blocked the activation of P38, ERK, and JNK. CP-25 combined with MTX/LEF exerts synergistic effects to inhibit inflammation of AA rats by inhibiting the MAPK pathway. In the other h...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-02, Vol.110, p.834-843
Hauptverfasser:	Yang, Xuezhi, Zhao, Yingjie, Jia, Xiaoyi, Wang, Chun, Wu, Yujing, Zhang, Lingling, Chang, Yan, Wei, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	CP-25 Drug combination GRK2 LEF MAPK MTX
Online-Zugang:	Volltext
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