Establishing a Multivariate Model for Predictable Antisense RNA-Mediated Repression

Recent advances in our understanding of RNA folding and functions have facilitated the use of regulatory RNAs such as synthetic antisense RNAs (asRNAs) to modulate gene expression. However, despite the simple and universal complementarity rule, predictable asRNA-mediated repression is still challeng...

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Veröffentlicht in:ACS synthetic biology 2019-01, Vol.8 (1), p.45-56
Hauptverfasser: Lee, Young Je, Kim, Soo-Jung, Amrofell, Matthew B, Moon, Tae Seok
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Sprache:eng
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