Carotid Endarterectomy with Autoarterial Remodeling of Bifurcation of the Common Carotid Artery and Carotid Endarterectomy with Patch Closure: Comparison of Methods

The objectives of our research were to identify whether the new method of carotid endarterectomy (CEA) with autoarterial remodeling of bifurcation of the common carotid artery (ARBCCA) influences daily parameters of blood pressure and heart rate (HR) while monitoring them on a daily basis and to ass...

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Veröffentlicht in:Journal of stroke and cerebrovascular diseases 2019-03, Vol.28 (3), p.741-750
Hauptverfasser: Ignatenko, Pavel, Novikova, Olga, Gostev, Alexander, Starodubtsev, Vladimir, Zeidlits, Galina, Kuznetsov, Konstantin, Starodubtseva, Alexandra, Karpenko, Andrey
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container_end_page 750
container_issue 3
container_start_page 741
container_title Journal of stroke and cerebrovascular diseases
container_volume 28
creator Ignatenko, Pavel
Novikova, Olga
Gostev, Alexander
Starodubtsev, Vladimir
Zeidlits, Galina
Kuznetsov, Konstantin
Starodubtseva, Alexandra
Karpenko, Andrey
description The objectives of our research were to identify whether the new method of carotid endarterectomy (CEA) with autoarterial remodeling of bifurcation of the common carotid artery (ARBCCA) influences daily parameters of blood pressure and heart rate (HR) while monitoring them on a daily basis and to assess the efficacy of the suggested method. It is a prospective randomized comparative study. The first group (n = 100) included patients that underwent ARBCCA, the second group (n = 100) included patients that underwent “classic” CEA with xenopericardial patch closure. Diurnal Holter recording of blood pressure and (HR) was performed before and after the surgical treatment in both groups. Surgical treatment in both groups leads to an increase of HR, arterial hypertension time index by systolic blood pressure, and arterial hypertension time index by diastolic arterial blood pressure. The damage of carotid artery bulb increases sympathetic innervation and causes dysregulation of the baroreceptor mechanism. In our study, we did not reveal a significant difference in the incidence of postoperative hypertension and the dependence of HR on the choice of surgical technique. Thus, the proposed ARBCCA method does not lead to an increased risk of pre-existing arterial hypertension development. A significant difference is found out on the parameter of the clamping time of carotid arteries in favor to ARBCCA group. Another advantage of the suggested technique is the number of restenosis greater than 50% during the 2-year follow-up (4 [4%] cases (ARBCCA group) versus 12 [12%] cases [“classic” CEA], respectively, P = .037).
doi_str_mv 10.1016/j.jstrokecerebrovasdis.2018.11.017
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subjects Aged
Arterial Pressure
Baroreflex
Carotid Artery Diseases - complications
Carotid Artery Diseases - diagnosis
Carotid Artery Diseases - physiopathology
Carotid Artery Diseases - surgery
Carotid Artery, Common - physiopathology
Carotid Artery, Common - surgery
Carotid endarterectomy
Constriction
diurnal Holter
Electrocardiography, Ambulatory
Endarterectomy, Carotid - adverse effects
Endarterectomy, Carotid - methods
Female
Heart Rate
Heterografts
Humans
Hypertension - diagnosis
Hypertension - etiology
Hypertension - physiopathology
Male
Middle Aged
Operative Time
Pericardium - transplantation
postoperative hypertension
Pressoreceptors - physiopathology
Prospective Studies
Risk Factors
Russia
Stroke - diagnosis
Stroke - etiology
Stroke - physiopathology
Stroke - prevention & control
stroke prevention
Time Factors
Treatment Outcome
title Carotid Endarterectomy with Autoarterial Remodeling of Bifurcation of the Common Carotid Artery and Carotid Endarterectomy with Patch Closure: Comparison of Methods
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