The Spontaneous Coronary Slow-Flow Phenomenon: Reversal by Intracoronary Nicardipine

An under-recognized cause of chest pain, the coronary slow-flow (CSF) phenomenon is characterized by delayed coronary opacification during diagnostic angiography in the absence of epicardial coronary artery disease (CAD). Given its angiographic resemblance to no-reflow during percutaneous coronary i...

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Veröffentlicht in:	The Journal of invasive cardiology 2019-03, Vol.31 (3), p.42-45
Hauptverfasser:	Mehta, Hetal H, Morris, Mackenzie, Fischman, David L, Finley, 4th, John J, Ruggiero, Nicholas, Walinsky, Paul, McCarey, Melissa, Savage, Michael P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angina Pectoris - diagnostic imaging Angina Pectoris - physiopathology Cohort Studies Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary Circulation - drug effects Female Humans Injections, Intra-Arterial Male Middle Aged Nicardipine - administration & dosage No-Reflow Phenomenon - diagnostic imaging No-Reflow Phenomenon - drug therapy Prognosis Recovery of Function Retrospective Studies Risk Assessment Treatment Outcome
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Zusammenfassung:	An under-recognized cause of chest pain, the coronary slow-flow (CSF) phenomenon is characterized by delayed coronary opacification during diagnostic angiography in the absence of epicardial coronary artery disease (CAD). Given its angiographic resemblance to no-reflow during percutaneous coronary intervention, a condition associated with microvascular spasm responsive to calcium-channel blockers, we hypothesized that spontaneous CSF may similarly be reversed by intracoronary (IC) nicardipine. The effect of IC nicardipine was evaluated in 30 patients. CSF was defined as spontaneously delayed flow (
ISSN:	1557-2501