Tmem30a deficiency leads to retinal rod bipolar cell degeneration

Phospholipids are asymmetrically distributed across the mammalian plasma membrane, with phosphatidylserine (PS) and phosphatidylethanolamine concentrated in the cytoplasmic leaflet of the membrane bilayer and phosphatidylcholine in the exoplasmic leaflet. This asymmetric distribution is dependent on...

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Veröffentlicht in:	Journal of neurochemistry 2019-02, Vol.148 (3), p.400-412
Hauptverfasser:	Yang, Yeming, Liu, Wenjing, Sun, Kuanxiang, Jiang, Li, Zhu, Xianjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis bipolar cell Bipolar cells Bipolar disorder Cell death Degeneration Dendritic structure Glial fibrillary acidic protein Gliosis Lecithin Mice Mortality Phosphatidylcholine Phosphatidylethanolamine Phosphatidylserine phosphatidylserine flippase Phospholipids Postsynaptic density proteins Protein kinase C Proteins Retina Retinal cells retinal degeneration Skewed distributions Staining Synaptic strength Synaptic transmission TMEM30A
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