TP53 mutations as potential prognostic markers for specific cancers: analysis of data from The Cancer Genome Atlas and the International Agency for Research on Cancer TP53 Database

Purpose Mutations in the tumor suppressor gene TP53 are associated with a variety of cancers. Therefore, it is important to know the occurrence and prognostic effects of TP53 mutations in certain cancers. Methods Over 29,000 cases from the April 2016 release of the International Agency for Research...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2019-03, Vol.145 (3), p.625-636
Hauptverfasser:	Li, Victor D., Li, Karen H., Li, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adenocarcinoma Breast cancer Cancer Research Clear cell-type renal cell carcinoma Codons Data processing Endometrial cancer Endometrium Exons Genomes Genomics Head & neck cancer Health risk assessment Hematology Hepatocellular carcinoma Internal Medicine Kidney cancer Leukemia Liver cancer Lung cancer Lung carcinoma Medical prognosis Medicine Medicine & Public Health Mutation Myeloid leukemia Oncology Original Article – Cancer Research p53 Protein Pancreas Pancreatic cancer Pancreatic carcinoma Squamous cell carcinoma Statistical analysis Thymoma Tumor suppressor genes Uterine cancer Uterus
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