MiR-92a inhibits fibroblast-like synoviocyte proliferation and migration in rheumatoid arthritis by targeting AKT2

Growing data have indicated that the miR-17–92 cluster is implicated in inflammatory response and rheumatoid arthritis (RA). This study was aimed to investigate the effects of miR-92a on the proliferation and migration of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Our results showe...

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Veröffentlicht in:	Journal of biosciences 2018-12, Vol.43 (5), p.911-919
Hauptverfasser:	Yu, Fang-Yuan, Xie, Cong-Qin, Jiang, Chang-liang, Sun, Ji-Tong, Feng, Hui-Cheng, Li, Chao, Huang, Xun-Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions AKT2 protein Arthritis Biomedical and Life Sciences Biomedicine Cell Biology Cell migration Cell proliferation Fibroblasts Inflammation Inflammatory response Kinases Life Sciences Microbiology Migrations Phosphorylation Plant Sciences Proliferation Proteins Reporter gene Restoration Rheumatoid arthritis siRNA Synoviocytes Tissue Zoology
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