Combined treatment with systemic resveratrol and resveratrol preconditioned mesenchymal stem cells, maximizes antifibrotic action in diabetic cardiomyopathy

Wnt/β‐catenin signaling pathway plays a crucial role in diabetic cardiomyopathy (DCM), thus we aimed at investigating the effect of one therapeutic approach with resveratrol (RSV) given systemically and combined treatment of RSV with mesenchymal stem cells (MSCs) that was either RSV‐preconditioned o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular physiology 2019-07, Vol.234 (7), p.10942-10963
Hauptverfasser:	ShamsEldeen, Asmaa Mohammed, Ashour, Hend, Shoukry, Heba Samy, Fadel, Mostafa, Kamar, Samaa Samir, Aabdelbaset, Marwan, Rashed, Laila Ahmed, Ammar, Hania Ibrahim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Apoptosis Attenuation Bone Malalignment Cardiomyopathy Catenin Cell culture Combined treatment Conditioning Culture media Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - complications Diabetic Cardiomyopathies - therapy Echocardiography Fibrosis Fibrosis - therapy Frizzled protein Heart Hypertrophy Male Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stem Cells - drug effects Mesenchyme Microvasculature preconditioned MSCs Preconditioning Proteins Random Allocation Rats Rats, Wistar Resveratrol Resveratrol - therapeutic use RSV sFRP2 and Wnt/β‐catenin Signal transduction Signaling Stem cells Streptozocin Wnt protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!