Increased risk of postoperative complications after total thyroidectomy with Graves' disease
Background The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear. Methods The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD grou...
Gespeichert in:
| Veröffentlicht in: | Head & neck 2019-02, Vol.41 (2), p.281-285 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 285 |
|---|---|
| container_issue | 2 |
| container_start_page | 281 |
| container_title | Head & neck |
| container_volume | 41 |
| creator | Kwon, Hyungju Kim, Jong‐kyu Lim, Woosung Moon, Byung‐In Paik, Nam Sun |
| description | Background
The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear.
Methods
The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD group) and 1:1 matched patients with euthyroid states (control group).
Results
The matched cohorts did not differ in age, sex, body mass index, pathologic diagnosis, and extent of operation. Excised thyroid weight was higher in the Graves' disease than in the control group (60.1 g vs 22.6 g; P |
| doi_str_mv | 10.1002/hed.25484 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2155162927</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2173520665</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3534-2e5bede7fae0b4d7bf97980920778e16945c6fd603e9085904cbc57a29bf6d663</originalsourceid><addsrcrecordid>eNp1kE1PGzEQQC3UCij00D9QWeqh5bAw68_4WFEKSEi9wK3SyuudVZzuxlvbSZR_j0PCBYmTx6Onp9Ej5EsNlzUAu5pjd8mkmIkjclqD0RVwoT_sZsErDlqckE8pLQCAK8GOyQkHyTWAOiV_75cuok3Y0ejTPxp6OoWUw4TRZr9G6sI4Dd6VT1gmavuMkeaQ7UDzfBuD79DlMG7pxuc5vY12jek77XzaOc_Jx94OCT8f3jPy9Pvm8fquevhze3_986FyXHJRMZQtdqh7i9CKTre90WYGhoHWM6yVEdKpvlPA0cBMGhCudVJbZtpedUrxM_Jj751i-L_ClJvRJ4fDYJcYVqlhtZS1Yobpgn57gy7CKi7LdYXSXDJQShbqYk-5GFKK2DdT9KON26aGZpe8Kcmbl-SF_XowrtqxbF_J18YFuNoDGz_g9n1Tc3fza698BlGjiso</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2173520665</pqid></control><display><type>article</type><title>Increased risk of postoperative complications after total thyroidectomy with Graves' disease</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Kwon, Hyungju ; Kim, Jong‐kyu ; Lim, Woosung ; Moon, Byung‐In ; Paik, Nam Sun</creator><creatorcontrib>Kwon, Hyungju ; Kim, Jong‐kyu ; Lim, Woosung ; Moon, Byung‐In ; Paik, Nam Sun</creatorcontrib><description>Background
The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear.
Methods
The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD group) and 1:1 matched patients with euthyroid states (control group).
Results
The matched cohorts did not differ in age, sex, body mass index, pathologic diagnosis, and extent of operation. Excised thyroid weight was higher in the Graves' disease than in the control group (60.1 g vs 22.6 g; P < .001). Multivariate analysis showed that Graves' disease significantly increased risks of transient RLN injury (odds ratio [OR] = 4.7, 95% confidence interval [CI] = 1.5‐15.5; P = .010) and transient hypoparathyroidism (OR = 2.8, 95% CI = 1.3‐5.8; P = .007). Rates of permanent complications were comparable in the Graves' disease and control groups.
Conclusions
Graves' disease can be a predictive factor for postoperative RLN injury and hypoparathyroidism after total thyroidectomy.</description><identifier>ISSN: 1043-3074</identifier><identifier>EISSN: 1097-0347</identifier><identifier>DOI: 10.1002/hed.25484</identifier><identifier>PMID: 30537006</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Body mass index ; complications ; Graves' disease ; Head and neck ; Hypoparathyroidism ; Multivariate analysis ; RLN injury ; Thyroid ; Thyroidectomy</subject><ispartof>Head & neck, 2019-02, Vol.41 (2), p.281-285</ispartof><rights>2018 Wiley Periodicals, Inc.</rights><rights>2019 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3534-2e5bede7fae0b4d7bf97980920778e16945c6fd603e9085904cbc57a29bf6d663</citedby><cites>FETCH-LOGICAL-c3534-2e5bede7fae0b4d7bf97980920778e16945c6fd603e9085904cbc57a29bf6d663</cites><orcidid>0000-0003-4979-8749</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fhed.25484$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fhed.25484$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30537006$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kwon, Hyungju</creatorcontrib><creatorcontrib>Kim, Jong‐kyu</creatorcontrib><creatorcontrib>Lim, Woosung</creatorcontrib><creatorcontrib>Moon, Byung‐In</creatorcontrib><creatorcontrib>Paik, Nam Sun</creatorcontrib><title>Increased risk of postoperative complications after total thyroidectomy with Graves' disease</title><title>Head & neck</title><addtitle>Head Neck</addtitle><description>Background
The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear.
Methods
The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD group) and 1:1 matched patients with euthyroid states (control group).
Results
The matched cohorts did not differ in age, sex, body mass index, pathologic diagnosis, and extent of operation. Excised thyroid weight was higher in the Graves' disease than in the control group (60.1 g vs 22.6 g; P < .001). Multivariate analysis showed that Graves' disease significantly increased risks of transient RLN injury (odds ratio [OR] = 4.7, 95% confidence interval [CI] = 1.5‐15.5; P = .010) and transient hypoparathyroidism (OR = 2.8, 95% CI = 1.3‐5.8; P = .007). Rates of permanent complications were comparable in the Graves' disease and control groups.
Conclusions
Graves' disease can be a predictive factor for postoperative RLN injury and hypoparathyroidism after total thyroidectomy.</description><subject>Body mass index</subject><subject>complications</subject><subject>Graves' disease</subject><subject>Head and neck</subject><subject>Hypoparathyroidism</subject><subject>Multivariate analysis</subject><subject>RLN injury</subject><subject>Thyroid</subject><subject>Thyroidectomy</subject><issn>1043-3074</issn><issn>1097-0347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kE1PGzEQQC3UCij00D9QWeqh5bAw68_4WFEKSEi9wK3SyuudVZzuxlvbSZR_j0PCBYmTx6Onp9Ej5EsNlzUAu5pjd8mkmIkjclqD0RVwoT_sZsErDlqckE8pLQCAK8GOyQkHyTWAOiV_75cuok3Y0ejTPxp6OoWUw4TRZr9G6sI4Dd6VT1gmavuMkeaQ7UDzfBuD79DlMG7pxuc5vY12jek77XzaOc_Jx94OCT8f3jPy9Pvm8fquevhze3_986FyXHJRMZQtdqh7i9CKTre90WYGhoHWM6yVEdKpvlPA0cBMGhCudVJbZtpedUrxM_Jj751i-L_ClJvRJ4fDYJcYVqlhtZS1Yobpgn57gy7CKi7LdYXSXDJQShbqYk-5GFKK2DdT9KON26aGZpe8Kcmbl-SF_XowrtqxbF_J18YFuNoDGz_g9n1Tc3fza698BlGjiso</recordid><startdate>201902</startdate><enddate>201902</enddate><creator>Kwon, Hyungju</creator><creator>Kim, Jong‐kyu</creator><creator>Lim, Woosung</creator><creator>Moon, Byung‐In</creator><creator>Paik, Nam Sun</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4979-8749</orcidid></search><sort><creationdate>201902</creationdate><title>Increased risk of postoperative complications after total thyroidectomy with Graves' disease</title><author>Kwon, Hyungju ; Kim, Jong‐kyu ; Lim, Woosung ; Moon, Byung‐In ; Paik, Nam Sun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3534-2e5bede7fae0b4d7bf97980920778e16945c6fd603e9085904cbc57a29bf6d663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Body mass index</topic><topic>complications</topic><topic>Graves' disease</topic><topic>Head and neck</topic><topic>Hypoparathyroidism</topic><topic>Multivariate analysis</topic><topic>RLN injury</topic><topic>Thyroid</topic><topic>Thyroidectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kwon, Hyungju</creatorcontrib><creatorcontrib>Kim, Jong‐kyu</creatorcontrib><creatorcontrib>Lim, Woosung</creatorcontrib><creatorcontrib>Moon, Byung‐In</creatorcontrib><creatorcontrib>Paik, Nam Sun</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Head & neck</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwon, Hyungju</au><au>Kim, Jong‐kyu</au><au>Lim, Woosung</au><au>Moon, Byung‐In</au><au>Paik, Nam Sun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased risk of postoperative complications after total thyroidectomy with Graves' disease</atitle><jtitle>Head & neck</jtitle><addtitle>Head Neck</addtitle><date>2019-02</date><risdate>2019</risdate><volume>41</volume><issue>2</issue><spage>281</spage><epage>285</epage><pages>281-285</pages><issn>1043-3074</issn><eissn>1097-0347</eissn><abstract>Background
The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear.
Methods
The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD group) and 1:1 matched patients with euthyroid states (control group).
Results
The matched cohorts did not differ in age, sex, body mass index, pathologic diagnosis, and extent of operation. Excised thyroid weight was higher in the Graves' disease than in the control group (60.1 g vs 22.6 g; P < .001). Multivariate analysis showed that Graves' disease significantly increased risks of transient RLN injury (odds ratio [OR] = 4.7, 95% confidence interval [CI] = 1.5‐15.5; P = .010) and transient hypoparathyroidism (OR = 2.8, 95% CI = 1.3‐5.8; P = .007). Rates of permanent complications were comparable in the Graves' disease and control groups.
Conclusions
Graves' disease can be a predictive factor for postoperative RLN injury and hypoparathyroidism after total thyroidectomy.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>30537006</pmid><doi>10.1002/hed.25484</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-4979-8749</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1043-3074 |
| ispartof | Head & neck, 2019-02, Vol.41 (2), p.281-285 |
| issn | 1043-3074 1097-0347 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2155162927 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Body mass index complications Graves' disease Head and neck Hypoparathyroidism Multivariate analysis RLN injury Thyroid Thyroidectomy |
| title | Increased risk of postoperative complications after total thyroidectomy with Graves' disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T13%3A21%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Increased%20risk%20of%20postoperative%20complications%20after%20total%20thyroidectomy%20with%20Graves'%20disease&rft.jtitle=Head%20&%20neck&rft.au=Kwon,%20Hyungju&rft.date=2019-02&rft.volume=41&rft.issue=2&rft.spage=281&rft.epage=285&rft.pages=281-285&rft.issn=1043-3074&rft.eissn=1097-0347&rft_id=info:doi/10.1002/hed.25484&rft_dat=%3Cproquest_cross%3E2173520665%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2173520665&rft_id=info:pmid/30537006&rfr_iscdi=true |