Symptomatic treatment of brain metastases in renal cell carcinoma with sorafenib
Brain metastasis is synchronous to the diagnosis of renal cell carcinoma (RCC). The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months...
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| Veröffentlicht in: | Journal of cancer research and therapeutics 2018, Vol.14, p.S1223-S1226 |
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| container_end_page | S1226 |
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| container_start_page | S1223 |
| container_title | Journal of cancer research and therapeutics |
| container_volume | 14 |
| creator | Hu, Dongyan Hu, Yu Li, Jisheng Wang, Xiuwen |
| description | Brain metastasis is synchronous to the diagnosis of renal cell carcinoma (RCC). The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months of 600 mg once daily sorafenib treatment who underwent right-sided nephrectomy. Further, withdrawal of sorafenib resulted in psychiatric changes along with increased metastasis lesions, which were recovered upon resuming the treatment, proposing that oral sorafenib can be used safely and efficiently for treatment of brain metastasis in advanced RCC. |
| doi_str_mv | 10.4103/0973-1482.189402 |
| format | Report |
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The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months of 600 mg once daily sorafenib treatment who underwent right-sided nephrectomy. 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The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months of 600 mg once daily sorafenib treatment who underwent right-sided nephrectomy. Further, withdrawal of sorafenib resulted in psychiatric changes along with increased metastasis lesions, which were recovered upon resuming the treatment, proposing that oral sorafenib can be used safely and efficiently for treatment of brain metastasis in advanced RCC.</abstract><doi>10.4103/0973-1482.189402</doi></addata></record> |
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| identifier | EISSN: 1998-4138 |
| ispartof | Journal of cancer research and therapeutics, 2018, Vol.14, p.S1223-S1226 |
| issn | 1998-4138 |
| language | eng |
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| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| title | Symptomatic treatment of brain metastases in renal cell carcinoma with sorafenib |
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