Low magnesium diet aggravates phosphate-induced kidney injury

Magnesium is known to protect against phosphate-induced tubular cell injuries in vitro. We investigated in vivo effects of magnesium on kidney injuries and phosphate metabolism in mice exposed to a high phosphate diet. Heminephrectomized mice were maintained on a high phosphate/normal magnesium diet...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2019-08, Vol.34 (8), p.1310-1319
Hauptverfasser:	Sakaguchi, Yusuke, Hamano, Takayuki, Matsui, Isao, Oka, Tatsufumi, Yamaguchi, Satoshi, Kubota, Keiichi, Shimada, Karin, Matsumoto, Ayumi, Hashimoto, Nobuhiro, Isaka, Yoshitaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diet - adverse effects Fibroblast Growth Factors - blood Glucuronidase - metabolism Kidney Diseases - blood Kidney Diseases - etiology Kidney Diseases - pathology Magnesium - administration & dosage Magnesium - blood Male Mice Mice, Inbred C57BL Parathyroid Hormone - blood Phosphates - blood Phosphates - toxicity
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