The irradiated human mandible: A quantitative study on bone vascularity

•Irradiation decreases mandibular vascular density and vascular number.•In local dosages exceeding 50 Gy, the proportion of smaller vessels decreases.•With increased time after radiotherapy, the proportion of smaller vessels decreases. Hypovascularisation is thought to play an important role in the...

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Veröffentlicht in:	Oral oncology 2018-12, Vol.87, p.126-130
Hauptverfasser:	Dekker, H., Bravenboer, N., van Dijk, D., Bloemena, E., Rietveld, D.H.F., ten Bruggenkate, Chr.M., Schulten, E.A.J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biopsy Bone Marrow - blood supply Bone Marrow - pathology Bone Marrow - radiation effects Case-Control Studies Dose-Response Relationship, Radiation Female Head and Neck Neoplasms - radiotherapy Humans Male Mandible Mandible - blood supply Mandible - pathology Mandible - radiation effects Mandibular Osteotomy Microvascular network Microvasculature Microvessel Middle Aged Oral cancer Osteoradionecrosis Osteoradionecrosis - etiology Osteoradionecrosis - pathology Osteoradionecrosis - surgery Radiation Dosage Radiotherapy Radiotherapy, Intensity-Modulated - adverse effects Time Factors
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