Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells

While the pluripotency of stem cells is known to determine the fate of embryonic development, the mechanisms underlying the acquisition and maintenance of full pluripotency largely remain elusive. Here, we show that the balance between mitochondrial fission and fusion is critical for the full plurip...

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Veröffentlicht in:Cell metabolism 2019-04, Vol.29 (4), p.979-992.e4
Hauptverfasser: Zhong, Xiuying, Cui, Peng, Cai, Yongping, Wang, Lihua, He, Xiaoping, Long, Peipei, Lu, Kangyang, Yan, Ronghui, Zhang, Ying, Pan, Xin, Zhao, Xiaoyang, Li, Wei, Zhang, Huafeng, Zhou, Qi, Gao, Ping
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Sprache:eng
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