Copulation-induced antinociception in female rats is blocked by atosiban, an oxytocin receptor antagonist

We hypothesized that copulation-induced temporary anti-nociception in female rats is mediated by the activation of central and/or peripheral oxytocin receptors. To test this hypothesis, we assessed the effects of intraperitoneal (ip), intrathecal (it), and intra-cerebroventricular (icv) administrati...

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Veröffentlicht in:	Hormones and behavior 2019-01, Vol.107, p.76-79
Hauptverfasser:	Gómora-Arrati, Porfirio, Gonzalez-Flores, Oscar, Galicia-Aguas, Yadira Leticia, Hoffman, Kurt Leroy, Komisaruk, Barry
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - metabolism Analgesics - pharmacology Animals Anti-nociception Atosiban Copulation Copulation - drug effects Copulation - physiology Estradiol - analogs & derivatives Estradiol - pharmacology Female Male Nociception - drug effects Nociception - physiology Oxytocin Oxytocin - metabolism Oxytocin - pharmacology Oxytocin receptor antagonist Progesterone - pharmacology Rats Rats, Sprague-Dawley Receptors, Oxytocin - antagonists & inhibitors Receptors, Oxytocin - metabolism Sex Factors Vasotocin - analogs & derivatives Vasotocin - pharmacology
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