Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway

Non-alcoholic steatohepatitis (NASH) is the hepatic manifestation of metabolic syndrome and is characterized by steatosis, inflammation, and fibrosis. We aim to characterize the hepatoprotective effects of Leonurine hydrochloride (LH) and the possible pathway in a cell and rodent model of diet-induc...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-02, Vol.110, p.571-581
Hauptverfasser:	Zhang, Li, Li, Hui-Xia, Pan, Wu-Si, Khan, Farhan Ullah, Qian, Cheng, Qi-Li, Feng-Rong, Xu, Xiaojun
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPK Fibrosis Inflammation Leonurine Non-alcoholic steatohepatitis Steatosis
Online-Zugang:	Volltext
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