Dynamic Generation of G‑Quadruplex DNA Ligands by Target-Guided Combinatorial Chemistry on a Magnetic Nanoplatform

Dynamic combinatorial chemistry (DCC) has emerged as a promising strategy for template-driven selection of high-affinity ligands for biological targets from equilibrating combinatorial libraries. However, only a few examples using disulfide-exchange-based DCC are reported for nucleic acid targets. H...

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Veröffentlicht in:	Journal of medicinal chemistry 2019-01, Vol.62 (2), p.762-773
Hauptverfasser:	Jana, Snehasish, Panda, Deepanjan, Saha, Puja, Pantos̨, G. Dan, Dash, Jyotirmayee
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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