Histologic and Ultrastructural Alterations in Lungs of Rats Exposed to Sub-lethal Concentrations of Hydrogen Sulfide

Fischer-344 rats were killed 1, 18, and 42 hr after a single 4-hr exposure to an atmosphere of 0, 116, or 615 mg m-3 of hydrogen sulfide (H2S). Lungs, fixed by the intratracheal route, were examined by light and electron microscopy. Histologic changes were transient and mainly present in rats expose...

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Veröffentlicht in:	Veterinary pathology 1988-09, Vol.25 (5), p.376-384
Hauptverfasser:	Lopez, A., Prior, M., Lilue, L. E., Gulayets, C., Atwal, O. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	alveolitis animal pathology Animals Capillaries - drug effects Capillaries - ultrastructure cytotoxicity edema electron microscopy endothelium histology hydrogen sulfide Hydrogen Sulfide - toxicity Lung - blood supply Lung - drug effects Lung - pathology Lung - ultrastructure lungs Male mast cells Microscopy, Electron mitosis necrosis Pulmonary Alveoli - drug effects Pulmonary Alveoli - pathology Pulmonary Alveoli - ultrastructure Pulmonary Edema - chemically induced Pulmonary Edema - pathology Random Allocation Rats Rats, Inbred F344
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