20+ Years and alive with primary myelofibrosis: Phenotypic signature of very long‐lived patients

In the last decade, several prognostic models for primary myelofibrosis (PMF) have been introduced and shown to be effective in predicting overall survival. The main objective for this study was to identify clinical and genetic markers of very long (20+ years) survival in PMF. A total of 1282 patien...

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Veröffentlicht in:	American journal of hematology 2019-03, Vol.94 (3), p.286-290
Hauptverfasser:	Penna, Domenico, Lasho, Terra L., Finke, Christy M., Vallapureddy, Rangit R., Hanson, Curtis A., Ketterling, Rhett P., Pardanani, Animesh, Gangat, Naseema, Tefferi, Ayalew
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Age Factors Aged Aged, 80 and over Bone Marrow - metabolism Bone Marrow - pathology Calreticulin - genetics Calreticulin - metabolism Female Genetic markers Health risk assessment Hematology Hemoglobin Hemoglobins - metabolism Humans Leukocyte Count Logistic Models Longitudinal Studies Male Males Middle Aged Mortality Mutation Myelofibrosis Phenotype Platelet Count Primary Myelofibrosis - diagnosis Primary Myelofibrosis - genetics Primary Myelofibrosis - mortality Primary Myelofibrosis - pathology Prognosis Repressor Proteins - genetics Repressor Proteins - metabolism Risk Factors Serine-Arginine Splicing Factors - genetics Serine-Arginine Splicing Factors - metabolism Sex Factors Splicing Factor U2AF - genetics Splicing Factor U2AF - metabolism Survival Analysis Survivors
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