A gold-catalyzed cycloisomerization/aerobic oxidation cascade strategy for 2-aryl indenones from 1,5-enynes
A unique gold(i)-catalyzed 5-endo-dig cyclization/aerobic oxidation cascade strategy from 1,5-enyne substrates with molecular oxygen as the oxidant to yield the indenone was described. The reaction mechanism was studied by heavy atom labelling and some related experiments. This method was applied to...
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| Veröffentlicht in: | Organic & biomolecular chemistry 2018-12, Vol.16 (47), p.9147-9151 |
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| container_end_page | 9151 |
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| container_issue | 47 |
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| container_title | Organic & biomolecular chemistry |
| container_volume | 16 |
| creator | Guo, Jia Peng, Xiaoshi Wang, Xiaoyu Xie, Fukai Zhang, Xinhang Liang, Guoduan Sun, Zenghui Liu, Yongxiang Cheng, Maosheng Liu, Yang |
| description | A unique gold(i)-catalyzed 5-endo-dig cyclization/aerobic oxidation cascade strategy from 1,5-enyne substrates with molecular oxygen as the oxidant to yield the indenone was described. The reaction mechanism was studied by heavy atom labelling and some related experiments. This method was applied to the formal total synthesis of isoprekinamycin. |
| doi_str_mv | 10.1039/c8ob02582g |
| format | Article |
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The reaction mechanism was studied by heavy atom labelling and some related experiments. 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| ispartof | Organic & biomolecular chemistry, 2018-12, Vol.16 (47), p.9147-9151 |
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| language | eng |
| recordid | cdi_proquest_miscellaneous_2150530751 |
| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Aromatic compounds Crystallography Gold Isomerization Labeling Oxidation Oxygen Reaction mechanisms Substrates |
| title | A gold-catalyzed cycloisomerization/aerobic oxidation cascade strategy for 2-aryl indenones from 1,5-enynes |
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