A nanobiological approach to nanotoxicology

A nanobiological approach to nanotoxicology

There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This articl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Human & experimental toxicology 2009-06, Vol.28 (6-7), p.393-400
Hauptverfasser: Nyland, JF, Silbergeld, EK
Format: Artikel
Sprache:eng
Schlagworte:
Health risk assessment
Molecular biology
Nanomaterials
Nanotechnology
Risk Assessment
Toxicology
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 400
container_issue 6-7
container_start_page 393
container_title Human & experimental toxicology
container_volume 28
creator Nyland, JF
Silbergeld, EK
description There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system’s biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.
doi_str_mv 10.1177/0960327109105161
format Article
fullrecord <record><control><sourceid>proquest_AFRWT</sourceid><recordid>TN_cdi_proquest_miscellaneous_21502895</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0960327109105161</sage_id><sourcerecordid>1860370881</sourcerecordid><originalsourceid>FETCH-LOGICAL-c394t-6e3439e43be99c297d9e3962a80574b5b459e585c183bfdea437d87e379224f3</originalsourceid><addsrcrecordid>eNp1kM1Lw0AQxRdRbK3ePUnx4EWis1_ZzLEUv6Dgpfew2UxqSpqt2QTsf29iC4WCpzm833vzeIzdcnji3JhnwBikMByQg-YxP2NjroyJAEGes_EgR4M-YlchrAEgRs0v2Yij0VppPmaPs2lta5-VvvKr0tlqarfbxlv3NW39n9T6n9IN6u6aXRS2CnRzuBO2fH1Zzt-jxefbx3y2iJxE1UYxSSWRlMwI0Qk0OZLEWNgEtFGZzpRG0ol2PJFZkZNV0uSJIWlQCFXICXvYx_Y9vjsKbbopg6OqsjX5LqSCaxAJ6h68PwHXvmvqvloqBCRGx3KAYA-5xofQUJFum3Jjm13KIR1GTE9H7C13h9wu21B-NBxW64FoDwS7ouPTfwN_AUGadrg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>220875635</pqid></control><display><type>article</type><title>A nanobiological approach to nanotoxicology</title><source>Sage Journals GOLD Open Access 2024</source><creator>Nyland, JF ; Silbergeld, EK</creator><creatorcontrib>Nyland, JF ; Silbergeld, EK</creatorcontrib><description>There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system’s biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.</description><identifier>ISSN: 0960-3271</identifier><identifier>EISSN: 1477-0903</identifier><identifier>DOI: 10.1177/0960327109105161</identifier><identifier>PMID: 19755451</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Health risk assessment ; Molecular biology ; Nanomaterials ; Nanotechnology ; Risk Assessment ; Toxicology</subject><ispartof>Human &amp; experimental toxicology, 2009-06, Vol.28 (6-7), p.393-400</ispartof><rights>SAGE Publications © Jun 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c394t-6e3439e43be99c297d9e3962a80574b5b459e585c183bfdea437d87e379224f3</citedby><cites>FETCH-LOGICAL-c394t-6e3439e43be99c297d9e3962a80574b5b459e585c183bfdea437d87e379224f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0960327109105161$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0960327109105161$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>315,781,785,21971,27858,27929,27930,44950,45338</link.rule.ids><linktorsrc>$$Uhttps://journals.sagepub.com/doi/full/10.1177/0960327109105161?utm_source=summon&amp;utm_medium=discovery-provider$$EView_record_in_SAGE_Publications$$FView_record_in_$$GSAGE_Publications</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19755451$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nyland, JF</creatorcontrib><creatorcontrib>Silbergeld, EK</creatorcontrib><title>A nanobiological approach to nanotoxicology</title><title>Human &amp; experimental toxicology</title><addtitle>Hum Exp Toxicol</addtitle><description>There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system’s biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.</description><subject>Health risk assessment</subject><subject>Molecular biology</subject><subject>Nanomaterials</subject><subject>Nanotechnology</subject><subject>Risk Assessment</subject><subject>Toxicology</subject><issn>0960-3271</issn><issn>1477-0903</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kM1Lw0AQxRdRbK3ePUnx4EWis1_ZzLEUv6Dgpfew2UxqSpqt2QTsf29iC4WCpzm833vzeIzdcnji3JhnwBikMByQg-YxP2NjroyJAEGes_EgR4M-YlchrAEgRs0v2Yij0VppPmaPs2lta5-VvvKr0tlqarfbxlv3NW39n9T6n9IN6u6aXRS2CnRzuBO2fH1Zzt-jxefbx3y2iJxE1UYxSSWRlMwI0Qk0OZLEWNgEtFGZzpRG0ol2PJFZkZNV0uSJIWlQCFXICXvYx_Y9vjsKbbopg6OqsjX5LqSCaxAJ6h68PwHXvmvqvloqBCRGx3KAYA-5xofQUJFum3Jjm13KIR1GTE9H7C13h9wu21B-NBxW64FoDwS7ouPTfwN_AUGadrg</recordid><startdate>200906</startdate><enddate>200906</enddate><creator>Nyland, JF</creator><creator>Silbergeld, EK</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7ST</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>SOI</scope></search><sort><creationdate>200906</creationdate><title>A nanobiological approach to nanotoxicology</title><author>Nyland, JF ; Silbergeld, EK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c394t-6e3439e43be99c297d9e3962a80574b5b459e585c183bfdea437d87e379224f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Health risk assessment</topic><topic>Molecular biology</topic><topic>Nanomaterials</topic><topic>Nanotechnology</topic><topic>Risk Assessment</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nyland, JF</creatorcontrib><creatorcontrib>Silbergeld, EK</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Environment Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environment Abstracts</collection><jtitle>Human &amp; experimental toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Nyland, JF</au><au>Silbergeld, EK</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A nanobiological approach to nanotoxicology</atitle><jtitle>Human &amp; experimental toxicology</jtitle><addtitle>Hum Exp Toxicol</addtitle><date>2009-06</date><risdate>2009</risdate><volume>28</volume><issue>6-7</issue><spage>393</spage><epage>400</epage><pages>393-400</pages><issn>0960-3271</issn><eissn>1477-0903</eissn><abstract>There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system’s biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>19755451</pmid><doi>10.1177/0960327109105161</doi><tpages>8</tpages></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 0960-3271
ispartof Human & experimental toxicology, 2009-06, Vol.28 (6-7), p.393-400
issn 0960-3271
1477-0903
language eng
recordid cdi_proquest_miscellaneous_21502895
source Sage Journals GOLD Open Access 2024
subjects Health risk assessment
Molecular biology
Nanomaterials
Nanotechnology
Risk Assessment
Toxicology
title A nanobiological approach to nanotoxicology
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-10T00%3A57%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_AFRWT&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20nanobiological%20approach%20to%20nanotoxicology&rft.jtitle=Human%20&%20experimental%20toxicology&rft.au=Nyland,%20JF&rft.date=2009-06&rft.volume=28&rft.issue=6-7&rft.spage=393&rft.epage=400&rft.pages=393-400&rft.issn=0960-3271&rft.eissn=1477-0903&rft_id=info:doi/10.1177/0960327109105161&rft_dat=%3Cproquest_AFRWT%3E1860370881%3C/proquest_AFRWT%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=220875635&rft_id=info:pmid/19755451&rft_sage_id=10.1177_0960327109105161&rfr_iscdi=true