Isoniazid-loaded chitosan/carbon nanotubes microspheres promote secondary wound healing of bone tuberculosis

Poor blood circulation makes it difficult for antitubercular drugs to achieve effective bactericidal concentration at tuberculose focus. The residual Mycobacterium tuberculosis around surgical wound would multiply, resulting in nonunion or sinus formation. Carbon nanotubes have strong tissue penetra...

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Veröffentlicht in:	Journal of biomaterials applications 2019-02, Vol.33 (7), p.989-996
Hauptverfasser:	Chen, Gangquan, Wu, Yaling, Yu, Dongping, Li, Rubing, Luo, Wenyuan, Ma, Guifu, Zhang, Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antitubercular Agents - administration & dosage Antitubercular Agents - therapeutic use Chitosan - chemistry Delayed-Action Preparations - chemistry Guinea Pigs Isoniazid - administration & dosage Isoniazid - therapeutic use Mycobacterium tuberculosis - drug effects Nanotubes, Carbon - chemistry Rats Tuberculosis, Osteoarticular - drug therapy Tuberculosis, Osteoarticular - pathology
Online-Zugang:	Volltext
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