Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ

[Display omitted] Sirtuin 1 (SIRT1) activation reduces oxidative stress, inhibits inflammatory responses, and retards cellular senescence in endothelial cells in mouse models of diabetes. However, whether SIRT1 also plays a protective role in vascular dysfunction of diabetic and obese mice is not fu...

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Veröffentlicht in:	Pharmacological research 2019-01, Vol.139, p.384-394
Hauptverfasser:	Cheang, Wai San, Wong, Wing Tak, Wang, Li, Cheng, Chak Kwong, Lau, Chi Wai, Ma, Ronald Chin Wan, Xu, Aimin, Wang, Nanping, Huang, Yu, Tian, Xiao Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Diet induced obesity Endothelial dysfunction PPARδ SIRT1
Online-Zugang:	Volltext
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