STAT3-induced upregulation of lncRNA CASC11 promotes the cell migration, invasion and epithelial-mesenchymal transition in hepatocellular carcinoma by epigenetically silencing PTEN and activating PI3K/AKT signaling pathway

Accumulating evidence suggest that long noncoding RNAs (lncRNAs) are dysregulated in various tumors and serve as crucial regulators in biological processes. Based on The Cancer Genome Atlas (TCGA) database, upregulation of CASC11 was associated with the low overall survival rate of patients with Hep...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-01, Vol.508 (2), p.472-479
Hauptverfasser:	Han, Yidi, Chen, Meizhu, Wang, Aili, Fan, Xiaoping
Format:	Artikel
Sprache:	eng
Schlagworte:	Hepatocellular carcinoma lncRNA CASC11 PI3K/AKT signaling pathway PTEN STAT3
Online-Zugang:	Volltext
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