Cadmium‐induced neurodegeneration and activation of noncanonical sonic hedgehog pathway in rat cerebellum

Background Cadmium is a nonessential toxic heavy metal, which enters the body easily and damages the cellular system. The sonic hedgehog (Shh) signaling pathway is one of the key regulatory pathways, which define neural growth and development. Objectives This study aimed to explore how cadmium expos...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biochemical and molecular toxicology 2019-04, Vol.33 (4), p.e22274-n/a
Hauptverfasser:	P. M., Mubeena Mariyath, Shahi, Mehdi H., Tayyab, Mohd, Farheen, Shirin, Khanam, Nabeela, Tabassum, Sartaj, Ali, Asif
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioassays Body weight Brain Cadmium Cerebellum Comet assay Damage Damage detection Deoxyribonucleic acid DNA DNA damage Fuel consumption Heavy metals Hedgehog protein Motor activity Neurodegeneration Nkx2.2 Oxidative stress Pax6 Polymerase chain reaction Rodents Signal transduction Signaling sonic hedgehog Structural integrity Toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!