The amyloid precursor protein (APP) processing as a biological link between Alzheimer's disease and cancer

Aging is a risk factor for several illnesses, such as Alzheimer's Disease and various cancers. However, an inverse correlation between malignancies and Alzheimer's Disease has been suggested. This review addressed the potential role of non-amyloidogenic and amyloidogenic pathways of amyloi...

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Veröffentlicht in:	Ageing research reviews 2019-01, Vol.49, p.83-91
Hauptverfasser:	Galvão, Jr, Fernando, Grokoski, Kamila Castro, da Silva, Bruno Batista, Lamers, Marcelo Lazzaron, Siqueira, Ionara Rodrigues
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - epidemiology Alzheimer Disease - etiology Alzheimer Disease - metabolism Amyloid beta-Peptides - metabolism Amyloid beta-Protein Precursor - metabolism Amyloid Precursor Protein Secretases - metabolism Animals Humans Neoplasms - epidemiology Neoplasms - etiology Neoplasms - metabolism
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