Inner- and outer-sphere binding of the minor groove site of adenine by alkali metal ions
A report on the preparation and molecular structures of Na sub(+) and K sub(+) complexes was presented. A range of models for probing the interaction of d-block metal ions with purine sites located in the minor groove of DNA were used. The compounds contained an additional metal ion-binding site tet...
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Veröffentlicht in: | Dalton : an international journal of inorganic chemistry 2002-01 (2), p.131-133 |
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container_title | Dalton : an international journal of inorganic chemistry |
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creator | Gibson, Ashleigh E. Price, Clayton Clegg, William Houlton, Andrew |
description | A report on the preparation and molecular structures of Na sub(+) and K sub(+) complexes was presented. A range of models for probing the interaction of d-block metal ions with purine sites located in the minor groove of DNA were used. The compounds contained an additional metal ion-binding site tethered at the position of the deoxyribose ring. Na sub(+) and K sub(+) ions exhibited different modes of interaction with the N3 site of the DNA base adenine in a model system. |
doi_str_mv | 10.1039/b108427p |
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A range of models for probing the interaction of d-block metal ions with purine sites located in the minor groove of DNA were used. The compounds contained an additional metal ion-binding site tethered at the position of the deoxyribose ring. Na sub(+) and K sub(+) ions exhibited different modes of interaction with the N3 site of the DNA base adenine in a model system.</description><subject>Alkali metals</subject><subject>Alkylation</subject><subject>Binding energy</subject><subject>Chemical bonds</subject><subject>Complexation</subject><subject>Electronic structure</subject><subject>Molecular structure</subject><subject>Positive ions</subject><subject>Potassium</subject><subject>Sodium</subject><issn>1472-7773</issn><issn>1364-5447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNo1kEtLAzEUhYMoWLTgT8hK3IzmncxSio9CwY2CuyGZ3GmDM8mYTIX-e6dUuYtzDufjLg5CN5TcU8LrB0eJEUyPZ2hBuRKVFEKfz15oVmmt-SValhIcIYTWRmuyQJ_rGCFX2EaP036abRl3kAG7EH2IW5w6PO0ADyGmjLc5pR_AJUxwLKyHGOLMHrDtv2wf8ACT7XFIsVyji872BZZ_eoU-np_eV6_V5u1lvXrcVC3Taqp0a2pupG5Z7WpPheKcyLbjwIhi3HXzzUl6pax0xnkJVPnak45bJ7gU_Ardnv6OOX3voUzNEEoLfW8jpH1pGBXGMM5n8O4EtjmVkqFrxhwGmw8NJc1xveZ_Pf4L2KVhwA</recordid><startdate>20020109</startdate><enddate>20020109</enddate><creator>Gibson, Ashleigh E.</creator><creator>Price, Clayton</creator><creator>Clegg, William</creator><creator>Houlton, Andrew</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20020109</creationdate><title>Inner- and outer-sphere binding of the minor groove site of adenine by alkali metal ions</title><author>Gibson, Ashleigh E. ; Price, Clayton ; Clegg, William ; Houlton, Andrew</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c276t-7c893857c29b9d1463305cf3e20623bfbfbcf35d66a5b8bd5e16d9d0f3ab43543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Alkali metals</topic><topic>Alkylation</topic><topic>Binding energy</topic><topic>Chemical bonds</topic><topic>Complexation</topic><topic>Electronic structure</topic><topic>Molecular structure</topic><topic>Positive ions</topic><topic>Potassium</topic><topic>Sodium</topic><toplevel>online_resources</toplevel><creatorcontrib>Gibson, Ashleigh E.</creatorcontrib><creatorcontrib>Price, Clayton</creatorcontrib><creatorcontrib>Clegg, William</creatorcontrib><creatorcontrib>Houlton, Andrew</creatorcontrib><collection>CrossRef</collection><jtitle>Dalton : an international journal of inorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gibson, Ashleigh E.</au><au>Price, Clayton</au><au>Clegg, William</au><au>Houlton, Andrew</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inner- and outer-sphere binding of the minor groove site of adenine by alkali metal ions</atitle><jtitle>Dalton : an international journal of inorganic chemistry</jtitle><date>2002-01-09</date><risdate>2002</risdate><issue>2</issue><spage>131</spage><epage>133</epage><pages>131-133</pages><issn>1472-7773</issn><eissn>1364-5447</eissn><abstract>A report on the preparation and molecular structures of Na sub(+) and K sub(+) complexes was presented. A range of models for probing the interaction of d-block metal ions with purine sites located in the minor groove of DNA were used. The compounds contained an additional metal ion-binding site tethered at the position of the deoxyribose ring. Na sub(+) and K sub(+) ions exhibited different modes of interaction with the N3 site of the DNA base adenine in a model system.</abstract><doi>10.1039/b108427p</doi><tpages>3</tpages></addata></record> |
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ispartof | Dalton : an international journal of inorganic chemistry, 2002-01 (2), p.131-133 |
issn | 1472-7773 1364-5447 |
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source | Royal Society of Chemistry Journals Archive (1841-2007); Alma/SFX Local Collection |
subjects | Alkali metals Alkylation Binding energy Chemical bonds Complexation Electronic structure Molecular structure Positive ions Potassium Sodium |
title | Inner- and outer-sphere binding of the minor groove site of adenine by alkali metal ions |
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