Poly-DL-lactide-poly(ethylene glycol) microspheres as oral and parenteral delivery systems for hepatitis B surface antigen

This project was aimed at illustrating the potential use of poly‐DL‐lactide–poly(ethylene glycol) (PELA) microspheres as a hepatitis B surface antigen (HBsAg) delivery system following subcutaneous (s.c.) or oral immunization over the current injection of an alum‐absorbed antigen. The antigen‐loadin...

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Veröffentlicht in:	Journal of applied polymer science 2002-01, Vol.83 (4), p.850-856
Hauptverfasser:	Li, Xiaohong, Zhou, Shaobing, Wu, Xiaorong, Yuan, Minglong, Liu, Li, Jia, Wenxiang, Deng, Xianmo, Huang, Zhitang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Applied sciences biodegradable Biodegradation Controlled drug delivery drug delivery systems Emulsions Enzymes Exact sciences and technology Immunization microencapsulation Organic polymers Particle size analysis Physicochemistry of polymers polyester Properties and characterization protein Proteins Solution and gel properties Solvent extraction
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