RP-hPLC/ESI MS determination of acyl chain positions in phospholipids

Since phospholipids are used as excipients in many pharmaceutical products, there is a need for validated strategies to characterize the phospholipid constituents. We describe a reversed phase HPLC/electrospray ionization mass spectrometry method that is an alternative to the laborious phospholipase...

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Veröffentlicht in:	Journal of separation science 2002-04, Vol.25 (5-6), p.285-289
Hauptverfasser:	Vernooij, Elisabeth A. A. M., Brouwers, Jos F. H. M., Kettenes-Van den Bosch, J. Jantina, Crommelin, Daan J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical chemistry Biological and medical sciences Chemistry Chromatographic analysis Chromatographic methods and physical methods associated with chromatography Drug products Electrospray ionization Exact sciences and technology General pharmacology Glycerol HPLC Ionization Mass spectrometry Medical sciences Other chromatographic methods Pharmacology. Drug treatments Phospholipids
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