Construction and expression of antibody targeted plasminogen activator

It has been known that antibody-mediated plasminogen activator will be much more specific than its parent molecular. To get a cheaper and more effective medicine for thrombolytic therapy, we used SZ51, a GMP140 specific monoclonal antibody, and a truncated single-chain urokinase to construct a novel...

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Veröffentlicht in:	Enzyme and microbial technology 2000-12, Vol.27 (10), p.755-760
Hauptverfasser:	Jiang, Peng-chen, Changgeng, Ruan, Ru, Bing-gen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody-targeted plasminogen activator Biological and medical sciences Biotechnology Enzyme kinetics Fundamental and applied biological sciences. Psychology Genes Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Miscellaneous Monoclonal antibodies Proteins Single-chain of fragments of variable region of antibody (scFv) Urokinase
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