Comparing the Potency of Chemicals with Multiple Modes of Action in Aquatic Toxicology: Acute Toxicity Due to Narcosis versus Reactive Toxicity of Acrylic Compounds

A series of acrylates and methacrylates was used to illustrate a strategy to compare the importance of two modes of action (MOA) and thereby identify the predominant cause of acute fish toxicity. Acrylic compounds are known to be Michael acceptors and may therefore react with glutathione (GSH), caus...

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Veröffentlicht in:	Environmental Science and Technology 1999-09, Vol.33 (17), p.3038-3043
Hauptverfasser:	Freidig, Andreas P, Verhaar, Henk J. M, Hermens, Joop L. M
Format:	Artikel
Sprache:	eng
Schlagworte:	ACRYLATES acrylic acid Acrylics Agnatha. Pisces Animal, plant and microbial ecology Applied ecology Biological and medical sciences BIOLOGICAL INDICATORS BIOLOGY AND MEDICINE, APPLIED STUDIES COMPARATIVE EVALUATIONS Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on vertebrates ENVIRONMENTAL SCIENCES Fish Fisheries FISHES Fundamental and applied biological sciences. Psychology glutathione Mathematical models METHACRYLATES methacrylic acid Modal analysis Pisces TOXICITY WATER CHEMISTRY WATER POLLUTION
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