A new ovine model of spine and chest wall deformity at birth with alteration of respiratory system mechanics and lung development: a feasibility study

Purpose To develop an animal model of spine and chest wall deformity (CWD) at birth and to evaluate its effects on respiratory system mechanics and lung development. Methods A spine and CWD was created in utero between 70 and 75 days of gestation in six ovine fetuses by resection of the seventh and...

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Veröffentlicht in:	European spine journal 2019-01, Vol.28 (1), p.114-120
Hauptverfasser:	Parent, Stefan, Samson, Nathalie, Shen, Jesse, Gutman, Gabriel, Bouchard, Sarah, Piedboeuf, Bruno, Praud, Jean-Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Birth Chest Disease Models, Animal Feasibility studies Female Fetus - abnormalities Fetus - physiopathology Fetuses Gestation Hypoplasia Lungs Mechanics Medicine Medicine & Public Health Musculoskeletal Abnormalities - physiopathology Neurosurgery Original Article Pregnancy Range of Motion, Articular Respiration Respiratory Mechanics Respiratory system Sheep Spine Spine - abnormalities Spine - physiopathology Surgical Orthopedics Thoracic Wall - abnormalities Thoracic Wall - physiopathology
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